Yankees vs White Sox Prediction and MLB Tips - 25 September 2025
Last updated: Sep 24, 2025, 11:11PM | Published: Sep 24, 2025, 6:28AM
The New York Yankees will face the Chicago White Sox in Game 191 of the American League Division Series at Yankee Stadium on Thursday, commencing at 9:05am AEST.
Max Fried (18-5, 2.92 ERA) will get the ball for the Yankees, while the White Sox will counter with Fraser Ellard (0-2, 4.50 ERA).
This article features Stats Insider's prediction and tips for the Yankees vs White Sox game, along with the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the outcome of Thursday's NY Yankees vs White Sox MLB game 10,000 times.
Our independent predictive analytics model currently gives the Yankees a 74% chance of defeating the White Sox at Yankee Stadium.
Yankees vs White Sox: Odds
The current betting odds in Australia for Thursday's MLB game at Yankee Stadium are shown here:
- Head to Head: Yankees $1.26, White Sox $4.00
- Line: Yankees -1.5 ($1.61), White Sox +1.5 ($2.40)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Yankees at $1.26 and the White Sox at $4.00.
The Yankees are listed as 1.5-run favourites against the White Sox, with odds of $1.61 available at TAB.
For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $2.40.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Yankees (-1.5) are predicted to cover the line 56% of the time, while the 8-run over/under is expected to go over 54% of the time.
Yankees vs White Sox: Best Bets
- Head to Head: White Sox at $4.00 with TAB
- Line: White Sox +1.5 at $2.40 with TAB
- Total Runs: Over 8 at $1.91 with TAB
These Yankees vs White Sox best bets are based on complex modelling and gambling expertise to help you place better bets with your chosen online bookie.
And while the Yankees have a higher chance of winning the game, betting on the White Sox to win is our preferred option because of the 1.8% edge identified when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is pivotal to being profitable in the long run.
Although the Yankees are more likely to cover the line, our best bet of White Sox +1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the best odds available.
Yankees vs White Sox: Prediction
Stats Insider provides full coverage of the NY Yankees vs White Sox game on Thursday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so refresh this page for the latest betting analysis before the NY Yankees vs White Sox match-up.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.
Yankees vs White Sox: Essential Details
The match-up between the Yankees and White Sox at Yankee Stadium is scheduled to begin at 9:05am AEST on Thursday.
- Teams: New York Yankees vs Chicago White Sox
- Date: Thursday 25 September 2025
- Time: 9:05am AEST
- Venue: Yankee Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our NY Yankees vs White Sox predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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