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White Sox vs Cardinals Prediction and MLB Tips - 18 June 2025

The Chicago White Sox will sqaure off with the St. Louis Cardinals in MLB action at Rate Field on Wednesday, commencing at 9:40am AEST.

Shane Smith (3-3, 2.37 ERA) will get the ball for the White Sox, pitting him against Matthew Liberatore (3-6, 4.17 ERA) for the Cardinals.

This article features Stats Insider's best betting tips for the White Sox vs Cardinals game, plus the latest betting odds in Australia.

Who Will Win?

Based on advanced machine learning and data, Stats Insider has simulated the outcome of Wednesday's White Sox vs St. Louis MLB game 10,000 times.

Our leading predictive analytics model currently gives the Cardinals a 54% chance of beating the White Sox at Rate Field.

White Sox vs Cardinals: Odds

The latest betting odds in Australia for Wednesday's MLB game at Rate Field are shown here:

  • Head to Head: White Sox $2.10, Cardinals $1.77
  • Line: White Sox +1.5 ($1.67), Cardinals -1.5 ($2.25)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the White Sox at $2.10 and the Cardinals at $1.77.

The White Sox are listed as 1.5-run underdogs against the Cardinals, with odds of $1.67 available at TAB.

For the favourite Cardinals (-1.5) to cover the line, TAB offers odds of $2.25.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the White Sox (+1.5) are predicted to cover the line 60% of the time, while the 9-run over/under is expected to stay under 57% of the time.

White Sox vs Cardinals: Betting Tips

  • Head to Head: White Sox at $2.10 with TAB
  • Line: White Sox +1.5 at $1.67 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

These White Sox vs Cardinals best bets are based on market-leading simulations and betting intelligence to help you place more informed bets with your chosen online bookie.

While the Cardinals have a higher chance of winning the game, betting on the White Sox to win is our preferred option because of the edge found when comparing our data-driven probabilities to the odds currently available.

Taking advantage of the edges published here at Stats Insider is one of the keys to achieving long-term profitability.

White Sox vs Cardinals: Prediction

Stats Insider provides full coverage of the White Sox vs St. Louis game on Wednesday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates regularly, so keep checking this page for the latest betting predictions before the White Sox vs St. Louis game.

As always, see Stats Insider's Best Bets to get betting tips on every MLB game, plus predictions for a wide range of other sports.

White Sox vs Cardinals: Essential Details

The match-up between the White Sox and Cardinals at Rate Field is scheduled to begin at 9:40am AEST on Wednesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our White Sox vs St. Louis predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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