Twins vs Yankees Prediction and MLB Tips - 17 September 2025
Last updated: Sep 16, 2025, 8:16PM | Published: Sep 15, 2025, 8:31PM
The Minnesota Twins will face the New York Yankees in MLB action at Target Field on Wednesday, starting at 9:40am AEST.
Zebby Matthews (4-5, 5.06 ERA) will start on the mound for the Twins, up against Cam Schlittler (3-3, 3.05 ERA) for the Yankees.
This article features Stats Insider's top betting tips for the Twins vs Yankees game, plus the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the result of Wednesday's Minnesota vs NY Yankees MLB game 10,000 times.
Our leading predictive analytics model gives the Yankees a 57% chance of beating the Twins at Target Field.
Twins vs Yankees: Odds
The latest betting odds in Australia for Wednesday's MLB game at Target Field are listed below:
- Head to Head: Twins $2.35, Yankees $1.62
- Line: Twins +1.5 ($1.80), Yankees -1.5 ($2.04)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Twins at $2.35 and the Yankees at $1.62.
The Twins are 1.5-run underdogs against the Yankees, with odds of $1.80 available at TAB.
For the favourite Yankees (-1.5) to cover the line, TAB offers odds of $2.04.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Twins (+1.5) are predicted to cover the line 55% of the time, while the 9-run over/under is expected to go over 51% of the time.
Twins vs Yankees: Best Bets
- Head to Head: Minnesota at $2.35 with TAB
- Line: Twins +1.5 at $1.80 with TAB
- Total Runs: Over 9 at $1.91 with TAB
Stats Insider's Twins vs Yankees best bets are based on world-class modelling and gambling intelligence to help you place more informed bets with your chosen online bookie.
While the Yankees have a higher chance of winning the game, betting on the Twins to win is our preferred option because of the 2.0% edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen on Stats Insider is one of the keys to achieving long-term success as a punter.
Twins vs Yankees: Prediction
Stats Insider provides full coverage of the Minnesota vs NY Yankees game on Wednesday, including data-driven predictions and expert tips.
Our model updates frequently, so refresh this article for the latest betting tips before the Minnesota vs NY Yankees match-up.
As always, see Stats Insider's Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.
Twins vs Yankees: Essential Details
The game between the Twins and Yankees at Target Field is scheduled to begin at 9:40am AEST on Wednesday.
- Teams: Minnesota Twins vs New York Yankees
- Date: Wednesday 17 September 2025
- Time: 9:40am AEST
- Venue: Target Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Minnesota vs NY Yankees predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.
