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Titans vs Panthers Prediction and Tips - NRL Round 22, 2025

The Titans will face the favoured Panthers in NRL Round 22 action at Cbus Super Stadium on Saturday, commencing at 3:00pm AEST.

This article features Stats Insider's prediction and tips for the Titans vs Panthers game, plus the latest betting odds and try scorer tips.

Who Will Win?

Using trusted computer power and data, Stats Insider has simulated the outcome of Saturday's Gold Coast vs Penrith NRL match 10,000 times.

Our leading predictive analytics model gives the Panthers an 82% chance of beating the Titans at Cbus Super Stadium.

Titans vs Panthers: Odds

The latest Bet365 betting odds for Saturday's NRL clash at Cbus Super Stadium are listed here:

  • Head to Head: Titans $5.00, Panthers $1.19
  • Line: Titans +14.5 ($1.91), Panthers -14.5 ($1.91)
  • Total (Over/Under 46.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Titans at $5.00 and the Panthers at $1.19.

The Titans are 14.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.

For the favourite Panthers (-14.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 46.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Titans (+14.5) are predicted to cover the line 52% of the time, while the 46.5-point over/under is expected to stay under 54% of the time.

Titans vs Panthers: Betting Tips

  • Head to Head: Titans at $5.00 with Bet365
  • Line: Titans +14.5 at $1.91 with Bet365
  • Total Points: Under 46.5 at $1.91 with Bet365

Stats Insider's Titans vs Panthers betting tips are based on complex modelling and gambling expertise to provide you with the best possible advice every day of the year.

While the Panthers have a higher chance of winning the game, betting on the Titans to win is our preferred option due to the edge found when comparing our data-driven probabilities to the odds currently available.

Making use of the edges seen here at Stats Insider is pivotal to being a profitable sports bettor in the long run.

Titans vs Panthers: Prediction

Stats Insider's predicted final score for Titans vs Panthers at Cbus Super Stadium this Saturday is the Panthers winning 30-16.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full betting coverage of the Titans vs Panthers match on Saturday, including data-driven predictions and live win probabilitiestips.

18+. Odds correct at time of publishing and subject to change.

Titans vs Panthers: Try Scorers

Looking for Titans vs Panthers try scorers? The data is in.

According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in Gold Coast vs Penrith.

To'o has a 8.9% chance of scoring the first try at Cbus Super Stadium, while the Panthers star has a 50.2% chance of scoring a try at any time during the match.

Scroll down for the complete list of first try scorer and anytime try scorer probabilities.

First Try Scorer Tips

Gold Coast Titans

  • Phillip Sami: 6.7% probability
  • Jaylan De: 4.8% probability
  • Jojo Fifita: 4.4% probability
  • AJ Brimson: 4.2% probability
  • Beau Fermor: 3.4% probability

Penrith Panthers

  • Brian To'o: 8.9% probability
  • Thomas Jenkins: 8.3% probability
  • Casey McLean: 6.5% probability
  • Izack Tago: 6.4% probability
  • Dylan Edwards: 6.3% probability

Anytime Try Scorer Tips

Gold Coast Titans

  • Phillip Sami: 41.5% probability
  • Jaylan De: 32.6% probability
  • Jojo Fifita: 30.6% probability
  • AJ Brimson: 27.8% probability
  • Beau Fermor: 25.5% probability

Penrith Panthers

  • Thomas Jenkins: 50.4% probability
  • Brian To'o: 50.2% probability
  • Casey McLean: 41.1% probability
  • Izack Tago: 38.9% probability
  • Dylan Edwards: 38.3% probability

Remember, our model updates frequently, so refresh this article for the latest betting analysis before the Titans vs Panthers game.

As always, see our Best Bets to get the best tips on every NRL match, plus predictions for a wide range of other sports.

Titans vs Panthers: Essential Details

The NRL Round 22 clash between the Titans and Panthers at Cbus Super Stadium is scheduled to commence at 3:00pm AEST on Saturday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Titans vs Panthers predictions are based on 10,000 data-driven simulations of the match, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our rugby league tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

If you purchase a product or register for an account through one of the links on our site, we may receive compensation.

More on the NRL

Stats Insider is your go-to source for betting on the NRL, with the latest NRL betting news, predictions for every NRL game, and futures odds for the NRL.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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