Titans vs Chiefs Prediction and Preview - NFL Week 16, 2025

The Tennessee Titans will face the Kansas City Chiefs in NFL Week 16 action at Nissan Stadium on Monday, starting at 5:00am AEDT.

This article features Stats Insider's top betting tips for the Titans vs Chiefs game, along with the latest betting odds and touchdown scorer tips.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Tennessee vs Kansas City NFL match-up 10,000 times.

Our proven predictive analytics model currently gives the Chiefs a 62% chance of beating the Titans at Nissan Stadium.

Titans vs Chiefs: Odds

The current Bet365 betting odds in Australia for Monday's NFL game at Nissan Stadium are listed below:

• Head to Head: Titans $2.50, Chiefs $1.56
• Line: Titans +3 ($1.91), Chiefs -3 ($1.91)
• Total (Over/Under 37.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Titans at $2.50 and the Chiefs at $1.56.

The Titans are listed as 3-point underdogs against the Chiefs, with odds of $1.91 available at Bet365.

For the favourite Chiefs (-3) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 37.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the bookmakers have got it right and both the Titans and the Chiefs have a 50% chance of covering the line.

The 37.5-point over/under is expected to go over 54% of the time.

Titans vs Chiefs: Betting Tips

• Head to Head: Kansas City at $1.56 with Bet365
• Line: Chiefs -3 at $1.91 with Bet365
• Total Points: Over 37.5 at $1.91 with Bet365

Today's Titans vs Chiefs best bets are based on market-leading modelling and gambling experience to bring you the best possible advice 24/7/365.

Titans vs Chiefs: Prediction

Stats Insider's predicted final score for Titans vs Chiefs at Nissan Stadium in Week 16 is the Chiefs prevailing 20-17.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full betting coverage of the Tennessee vs Kansas City game in Week 16, including data-driven predictions and live win probabilitiestips.

Get expert analysis from the US with Dimers' in-depth Titans vs Chiefs prediction.

18+. Odds correct at time of publishing and subject to change.

Titans vs Chiefs: TD Scorer Tips

Who will score the first touchdown in Titans vs Chiefs? The data is in.

According to Stats Insider, Kansas City's Kareem Hunt is the most likely player to score the first TD in Titans vs Chiefs.

Hunt has a 9.5% chance of scoring the first TD at Nissan Stadium, while the Chiefs RB has a 38.7% chance of scoring an anytime touchdown.

Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.

First Touchdown Scorer Tips

Titans First TD Tips

• Tony Pollard: 8.3% probability
• Tyjae Spears: 7.2% probability
• Chimere Dike: 7.2% probability
• Elic Ayomanor: 6.2% probability
• Gunnar Helm: 4.3% probability

Chiefs First TD Tips

• Kareem Hunt: 9.5% probability
• Xavier Worthy: 6.9% probability
• Hollywood Brown: 6.4% probability
• Isiah Pacheco: 6.2% probability
• Travis Kelce: 6.2% probability

Anytime Touchdown Scorer Tips

Titans Anytime TD Tips

• Tony Pollard: 27.2% probability
• Tyjae Spears: 24.2% probability
• Chimere Dike: 24.1% probability
• Elic Ayomanor: 21.1% probability
• Gunnar Helm: 15.1% probability

Chiefs Anytime TD Tips

• Kareem Hunt: 38.7% probability
• Xavier Worthy: 30.2% probability
• Hollywood Brown: 28.1% probability
• Isiah Pacheco: 27.5% probability
• Travis Kelce: 27.4% probability

Titans-Chiefs Projected Player Stats

Of the starting quarterbacks, the Titans' Cam Ward is projected for 189 passing yards. The Chiefs' Gardner Minshew is expected to throw for 219 yards.

Titans Starting QB

• Cam Ward: 189 projected passing yards

Chiefs Starting QB

• Gardner Minshew: 219 projected passing yards

Titans Rushing Yards

• Tony Pollard: 59 projected yards
• Tyjae Spears: 19 projected yards
• Cam Ward: 11 projected yards

Chiefs Rushing Yards

• Isiah Pacheco: 39 projected yards
• Kareem Hunt: 32 projected yards
• Gardner Minshew: 9 projected yards

Titans Receiving Yards

• Chimere Dike: 34 projected yards
• Elic Ayomanor: 30 projected yards
• Chig Okonkwo: 28 projected yards
• Gunnar Helm: 27 projected yards
• Van Jefferson: 26 projected yards

Chiefs Receiving Yards

• Travis Kelce: 51 projected yards
• Xavier Worthy: 48 projected yards
• Hollywood Brown: 42 projected yards
• JuJu Smith-Schuster: 26 projected yards
• Noah Gray: 19 projected yards

Remember, our model updates frequently, so refresh this article for the latest betting analysis before the Tennessee vs Kansas City match-up.

As always, see our Best Bets for the best tips on every NFL game, as well as predictions for a wide range of other sports.

Titans vs Chiefs: Week 16 Essential Details

The NFL Week 16 game between the Titans and Chiefs at Nissan Stadium is scheduled to begin at 5:00am AEDT on Monday.

• Teams: Tennessee Titans vs Kansas City Chiefs
• Date: Monday 22 December 2025
• Time: 5:00am AEDT
• Venue: Nissan Stadium

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our Tennessee vs Kansas City predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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