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Tigers vs Guardians Prediction and MLB Tips - 25 May 2025

The Detroit Tigers will sqaure off with the Cleveland Guardians in MLB action at Comerica Park on Sunday, commencing at 9:15am AEST.

Casey Mize (6-1, 2.53 ERA) will get the ball for the Tigers, while the Guardians will counter with Luis L. Ortiz (2-5, 4.66 ERA).

This article features Stats Insider's prediction and tips for the Tigers vs Guardians game, as well as the latest betting odds in Australia.

Who Will Win?

Using trusted computer power and data, Stats Insider has simulated the result of Sunday's Detroit vs Cleveland MLB game 10,000 times.

Our proven predictive analytics model currently gives the Tigers a 56% chance of defeating the Guardians at Comerica Park.

Tigers vs Guardians: Odds

The latest betting odds in Australia for Sunday's MLB game at Comerica Park are shown here:

  • Head to Head: Tigers $1.71, Guardians $2.20
  • Line: Tigers -1.5 ($2.50), Guardians +1.5 ($1.56)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Tigers at $1.71 and the Guardians at $2.20.

The Tigers are listed as 1.5-run favourites against the Guardians, with odds of $2.50 available at TAB.

For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.56.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Guardians (+1.5) are predicted to cover the line 62% of the time, while the 8.5-run over/under is expected to stay under 52% of the time.

Tigers vs Guardians: Best Bets

  • Head to Head: Cleveland at $2.20 with TAB
  • Line: Guardians +1.5 at $1.56 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

These Tigers vs Guardians betting tips are based on detailed simulations and gambling experience to bring you the best possible advice around the clock.

While the Tigers have a higher chance of winning the game, betting on the Guardians to win is our preferred option because of the edge found when comparing our data-led probabilities to the odds currently available.

Making use of the edges seen on Stats Insider is crucial to achieving long-term success as a punter.

Tigers vs Guardians: Prediction

Stats Insider provides full coverage of the Detroit vs Cleveland game on Sunday, including data-driven predictions and free betting tips.

Our model updates frequently, so refresh this page for the latest betting predictions before the Detroit vs Cleveland game.

As always, see our Best Bets for the best tips for every MLB game, plus predictions for a wide range of other sports.

Tigers vs Guardians: Essential Details

The game between the Tigers and Guardians at Comerica Park is scheduled to begin at 9:15am AEST on Sunday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Detroit vs Cleveland predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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