Tigers vs Brewers Prediction and MLB Tips - 22 April 2026
Last updated: Apr 21, 2026, 10:41PM | Published: Apr 20, 2026, 5:33PM
The Detroit Tigers will take on the Milwaukee Brewers in MLB action at Comerica Park on Wednesday, beginning at 8:40am AEST.
The Tigers will send Keider Montero (1-1, 3.31 ERA) to the mound, while the Brewers are going with Kyle Harrison (1-1, 3.07 ERA).
This article features Stats Insider's free betting tips for the Tigers vs Brewers game, along with the latest betting odds in Australia.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Wednesday's Detroit vs Milwaukee MLB game 10,000 times.
Our proven predictive analytics model currently gives the Tigers a 51% chance of winning against the Brewers at Comerica Park.
Tigers vs Brewers: Odds
The current betting odds in Australia for Wednesday's MLB game at Comerica Park are shown below:
- Head to Head: Tigers $1.91, Brewers $1.91
- Line: Tigers -1.5 ($2.79), Brewers +1.5 ($1.46)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Tigers at $1.91 and the Brewers at $1.91.
The Tigers are 1.5-run favourites against the Brewers, with odds of $2.79 available at TAB.
For the underdog Brewers (+1.5) to cover the line, TAB offers odds of $1.46.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Brewers (+1.5) are predicted to cover the line 65% of the time, while the 8-run over/under is expected to go over 54% of the time.
Tigers vs Brewers: Best Bets
- Head to Head: Detroit at $1.91 with TAB
- Line: Tigers -1.5 at $2.79 with TAB
- Total Runs: Over 8 at $1.91 with TAB
Stats Insider's Tigers vs Brewers betting tips are based on detailed modelling and betting experience to help you place better bets with your chosen online bookie.
Even though the Brewers are more likely to cover the line, our best bet of Tigers -1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the best odds available.
Tigers vs Brewers: Prediction
Stats Insider provides full betting coverage of the Detroit vs Milwaukee game on Wednesday, including data-driven predictions and live win probabilitiestips.
Our model updates regularly, so keep checking this page for the latest betting predictions before the Detroit vs Milwaukee match-up.
As always, see Stats Insider's Best Bets for the best tips for every MLB game, plus predictions for a wide range of other sports.
Tigers vs Brewers: Essential Details
The match-up between the Tigers and Brewers at Comerica Park is scheduled to start at 8:40am AEST on Wednesday.
- Teams: Detroit Tigers vs Milwaukee Brewers
- Date: Wednesday 22 April 2026
- Time: 8:40am AEST
- Venue: Comerica Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Detroit vs Milwaukee predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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