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Texans vs 49ers Prediction and Preview - NFL Week 8, 2025

The Houston Texans will face the San Francisco 49ers in NFL Week 8 action at NRG Stadium on Monday, October 27, beginning at 4:00am AEDT.

This article features Stats Insider's best betting tips for the Texans vs 49ers game, plus the latest betting odds in Australia.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the result of 49ers vs Texans 10,000 times.

Our independent predictive analytics model gives the 49ers a 59% chance of defeating the Texans at NRG Stadium.

Texans vs 49ers: Odds

The latest Bet365 betting odds in Australia for this NFL game at NRG Stadium are shown below:

  • Head to Head: Texans $1.77, 49ers $2.10
  • Line: Texans -2 ($1.91), 49ers +2 ($1.91)
  • Total (Over/Under 43.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Texans at $1.77 and the 49ers at $2.10.

The Texans are 2-point favourites against the 49ers, with odds of $1.91 available at Bet365.

For the underdog 49ers (+2) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 43.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the 49ers (+2) are predicted to cover the line 63% of the time, while the 43.5-point over/under is expected to stay under 51% of the time.

Texans vs 49ers: Best Bets

  • Head to Head: San Francisco at $2.10 with Bet365
  • Line: 49ers +2 at $1.91 with Bet365
  • Total Points: Under 43.5 at $1.91 with Bet365

When you see a 🔥, that means you've found one of Stats Insider's best tips for today across any sport.

Our Texans vs 49ers best bets are based on detailed modelling and gambling expertise to provide you with the best possible advice around the clock.

Texans vs 49ers: Prediction

Stats Insider's predicted final score for Texans vs 49ers at NRG Stadium in Week 8 is the 49ers winning 23-20.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the Houston vs San Francisco game in Week 8, including data-driven predictions and expert tips.

18+. Odds correct at time of publishing and subject to change.

Remember, our model updates regularly, so keep checking this page for the latest betting predictions before the Houston vs San Francisco match-up.

As always, see Stats Insider's Best Bets to get the best tips for every NFL game, as well as predictions for a wide range of other sports.

Texans vs 49ers: Week 8 Essential Details

The NFL Week 8 match-up between the Texans and 49ers at NRG Stadium is scheduled to begin at 4:00am AEDT on Monday, October 27.

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our Houston vs San Francisco predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our NFL predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on NFL

Stats Insider is your home for betting on the NFL in Australia, with the latest NFL betting news, predictions for every NFL game, and Super Bowl odds for the NFL.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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