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Stefanos Tsitsipas vs Alexandre Muller Prediction - US Open 2025

Stefanos Tsitsipas will take on Alexandre Muller in the first round of the US Open Men's Singles 2025 on Wednesday.

This article features Stats Insider's prediction and tips for the Tsitsipas vs Muller match, along with the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Wednesday's Tsitsipas-Muller men's singles match 10,000 times.

Our independent predictive analytics model gives Tsitsipas a 63% chance of beating Muller in the US Open Men's Singles 2025.

Tsitsipas vs Muller: Odds

The latest betting odds in Australia for Wednesday's US Open 2025 match between Tsitsipas and Muller are shown here:

  • Head to Head: Tsitsipas $1.53, Muller $2.50
  • First Set: Tsitsipas $1.66, Muller $2.20

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, TAB currently has Tsitsipas at $1.53 and Muller at $2.50.

TAB currently has odds for Tsitsipas to win the first set at $1.66 and odds for Muller to win the first set at $2.20.

Tsitsipas vs Muller: Betting Tips

  • Head to Head: Tsitsipas at $1.53 with TAB
  • First Set: Muller at $1.80 with TAB (55% probability)

These Stefanos Tsitsipas vs Alexandre Muller best bets are based on detailed simulations and gambling expertise to help you place better bets with your chosen online bookie.

While Tsitsipas is more likely to win the first set on this occassion, our recommended bet of Muller ($1.80) is based on the chance of that happening, per our model, and the betting odds currently available.

Tsitsipas vs Muller: Prediction

Stats Insider provides full coverage of the Stefanos Tsitsipas vs Alexandre Muller match at the US Open 2025 tournament, including data-driven predictions and expert tips.

Remember, our model updates frequently, so keep checking this page for the latest betting analysis before the Tsitsipas-Muller match in the US Open Men's Singles 2025.

As always, see our Best Bets for betting tips for every tennis match, as well as predictions for a wide range of other sports.

Tsitsipas vs Muller: US Open 2025 Essential Details

The US Open 2025 match between Stefanos Tsitsipas and Alexandre Muller is scheduled to commence at 6:30am AEST.

  • Match: Stefanos Tsitsipas vs Alexandre Muller
  • Date: Wednesday 27 August 2025
  • Approx. Time: 6:30am AEST
  • Event: US Open Men's Singles 2025
  • Round: First round

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Stefanos Tsitsipas vs Alexandre Muller predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our tennis tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our tennis predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on Tennis

Stats Insider is your home for betting on tennis in Australia, with the latest tennis betting news, tips for every tennis tournament, and our in-house approach to accurately ranking the world's top 100 men's and women's players.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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