Steelers vs Bills Prediction and Preview - NFL Week 13, 2025
Last updated: Nov 30, 2025, 9:25PM | Published: Nov 23, 2025, 7:44AM
The Pittsburgh Steelers will sqaure off with the Buffalo Bills in NFL Week 13 action at Acrisure Stadium on Monday, beginning at 8:25am AEDT.
This article features Stats Insider's top betting tips for the Steelers vs Bills game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Monday's Pittsburgh vs Buffalo NFL game 10,000 times.
Our proven predictive analytics model currently gives the Bills a 62% chance of defeating the Steelers in Week 13 of the NFL season.
Steelers vs Bills: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Acrisure Stadium are listed below:
- Head to Head: Steelers $2.45, Bills $1.59
- Line: Steelers +3 ($1.91), Bills -3 ($1.91)
- Total (Over/Under 44.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Steelers at $2.45 and the Bills at $1.59.
The Steelers are 3-point underdogs against the Bills, with odds of $1.91 available at Bet365.
For the favourite Bills (-3) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 44.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the bookmakers have got it right and both the Steelers and the Bills have a 50% chance of covering the line.
The 44.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.
Steelers vs Bills: Best Bets
- Head to Head: Buffalo at $1.59 with Bet365
- Line: Bills -3 at $1.91 with Bet365
- Total Points: Under 44.5 at $1.91 with Bet365
Today's Steelers vs Bills betting tips are based on complex modelling and wagering expertise to help you place better bets with your chosen online bookie.
Steelers vs Bills: Prediction
Stats Insider's predicted final score for Steelers vs Bills at Acrisure Stadium in Week 13 is the Bills winning 23-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Pittsburgh vs Buffalo game in Week 13, including data-driven predictions and expert tips.
For in-depth analysis from US experts,, check out Dimers' detailed Steelers vs Bills prediction.
18+. Odds correct at time of publishing and subject to change.Steelers vs Bills: TD Scorer Tips
Who will score an anytime touchdown in Steelers vs Bills? The latest data is in.
According to Stats Insider, Buffalo's James Cook is the most likely player to score the first touchdown in Steelers vs Bills.
Cook has a 10.4% chance of scoring the first TD at Acrisure Stadium, while the Bills RB has a 47.7% chance of scoring an anytime touchdown.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Steelers First TD Tips
- Jaylen Warren: 8.7% probability
- DK Metcalf: 7.3% probability
- Kenneth Gainwell: 7.1% probability
- Calvin Austin: 4.2% probability
- Jonnu Smith: 4.0% probability
Bills First TD Tips
- James Cook: 10.4% probability
- Josh Allen: 8.6% probability
- Khalil Shakir: 6.1% probability
- Gabe Davis: 4.0% probability
- Dawson Knox: 3.9% probability
Anytime Touchdown Scorer Tips
Steelers Anytime TD Tips
- Jaylen Warren: 38.7% probability
- DK Metcalf: 33.5% probability
- Kenneth Gainwell: 32.9% probability
- Calvin Austin: 21.0% probability
- Jonnu Smith: 20.2% probability
Bills Anytime TD Tips
- James Cook: 47.7% probability
- Josh Allen: 41.5% probability
- Khalil Shakir: 31.4% probability
- Gabe Davis: 21.9% probability
- Dawson Knox: 21.7% probability
Steelers-Bills Projected Player Stats
Of the starting quarterbacks, the Steelers' Aaron Rodgers is projected for 208 passing yards, while the Bills' Josh Allen is expected to throw for 239 yards.
Steelers Starting QB
- Aaron Rodgers: 208 projected passing yards
Bills Starting QB
- Josh Allen: 239 projected passing yards
Steelers Rushing Yards
- Jaylen Warren: 65 projected yards
- Kenneth Gainwell: 32 projected yards
- Kaleb Johnson: 5 projected yards
Bills Rushing Yards
- James Cook: 86 projected yards
- Josh Allen: 32 projected yards
- Ty Johnson: 12 projected yards
Steelers Receiving Yards
- DK Metcalf: 52 projected yards
- Calvin Austin: 33 projected yards
- Pat Freiermuth: 23 projected yards
- Kenneth Gainwell: 22 projected yards
- Jonnu Smith: 21 projected yards
Bills Receiving Yards
- Khalil Shakir: 57 projected yards
- Gabe Davis: 32 projected yards
- Dawson Knox: 30 projected yards
- Keon Coleman: 29 projected yards
- Tyrell Shavers: 26 projected yards
Remember, our model updates frequently, so refresh this page for the latest betting predictions before the Pittsburgh vs Buffalo match-up.
As always, see Stats Insider's Best Bets to get the best tips for every NFL game, plus predictions for a wide range of other sports.
Steelers vs Bills: Week 13 Essential Details
The NFL Week 13 match-up between the Steelers and Bills at Acrisure Stadium is scheduled to commence at 8:25am AEDT on Monday.
- Teams: Pittsburgh Steelers vs Buffalo Bills
- Date: Monday 1 December 2025
- Time: 8:25am AEDT
- Venue: Acrisure Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Pittsburgh vs Buffalo predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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