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St Kilda vs North Melbourne Prediction and Tips - AFL Round 21, 2025

St Kilda will sqaure off with North Melbourne in AFL Round 21 action at Marvel Stadium on Sunday, commencing at 1:40pm AEST.

This article features Stats Insider's prediction and tips for the St Kilda vs North Melbourne game, along with the latest betting odds.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the outcome of Sunday's St Kilda vs North Melbourne AFL match 10,000 times.

Our proven predictive analytics model gives the Saints an 81% chance of winning against the Kangaroos at Marvel Stadium.

St Kilda vs North Melbourne: Odds

The latest Bet365 betting odds for Sunday's AFL clash at Marvel Stadium are shown here:

  • Head to Head: St Kilda $1.28, North Melbourne $3.85
  • Line: St Kilda -24.5 ($1.91), North Melbourne +24.5 ($1.91)
  • Total (Over/Under 179.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has St Kilda at $1.28 and North Melbourne at $3.85.

The Saints are listed as 24.5-point favourites against the Kangaroos, with odds of $1.91 available at Bet365.

For the underdog Kangaroos (+24.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 179.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the bookmakers have got it right and both St Kilda and North Melbourne have a 50% chance of covering the line.

The 179.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.

St Kilda vs North Melbourne: Best Bets

  • Head to Head: St Kilda at $1.28 with Bet365
  • Line: N Melbourne +24.5 at $1.91 with Bet365
  • Total Points: Under 179.5 at $1.91 with Bet365

Today's St Kilda vs North Melbourne best bets are based on detailed modelling and betting expertise to provide you with the best possible advice around the clock.

St Kilda vs North Melbourne: Prediction

Stats Insider's predicted final score for St Kilda vs North Melbourne at Marvel Stadium on Sunday is St Kilda prevailing 101-77.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full betting coverage of the St Kilda vs North Melbourne match on Sunday, including data-driven predictions and the best betting tips.

18+. Odds correct at time of publishing and subject to change.

Remember, our model updates frequently, so keep checking this article for the latest betting tips before the St Kilda vs North Melbourne match.

As always, see Stats Insider's Best Bets for betting tips on every AFL match, as well as predictions for a wide range of other sports.

St Kilda vs North Melbourne: Essential Details

The AFL Round 21 clash between the Saints and Kangaroos at Marvel Stadium is scheduled to commence at 1:40pm AEST on Sunday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our St Kilda vs North Melbourne predictions have been made thanks to 10,000 data-driven simulations of the match, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our AFL tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on the AFL

Stats Insider is your home for betting on the AFL, with the latest AFL betting news, tips for every AFL game, and futures odds for the AFL.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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