St Kilda vs North Melbourne Prediction and Tips - AFL Round 21, 2025

St Kilda will sqaure off with North Melbourne in AFL Round 21 action at Marvel Stadium on Sunday, starting at 1:40pm AEST.

This article features Stats Insider's prediction and tips for the St Kilda vs North Melbourne game, plus the latest betting odds.

Who Will Win?

Using advanced machine learning and data, Stats Insider has simulated the result of Sunday's St Kilda vs North Melbourne AFL match 10,000 times.

Our independent predictive analytics model currently gives the Saints an 80% chance of defeating the Kangaroos in Round 21 of the 2025 AFL season.

St Kilda vs North Melbourne: Odds

The current Bet365 betting odds for Sunday's AFL clash at Marvel Stadium are listed below:

• Head to Head: St Kilda $1.23, North Melbourne $4.20
• Line: St Kilda -25.5 ($1.91), North Melbourne +25.5 ($1.91)
• Total (Over/Under 176.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has St Kilda at $1.23 and North Melbourne at $4.20.

The Saints are 25.5-point favourites against the Kangaroos, with odds of $1.91 available at Bet365.

For the underdog Kangaroos (+25.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 176.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Kangaroos (+25.5) are predicted to cover the line 53% of the time, while the 176.5-point over/under is expected to stay under 53% of the time.

St Kilda vs North Melbourne: Best Bets

• Head to Head: St Kilda at $1.23 with Bet365
• Line: N Melbourne +25.5 at $1.91 with Bet365
• Total Points: Under 176.5 at $1.91 with Bet365

Stats Insider's St Kilda vs North Melbourne betting tips are based on complex modelling and betting intelligence to help you place smarter bets with your chosen online bookie.

St Kilda vs North Melbourne: Prediction

Stats Insider's predicted final score for St Kilda vs North Melbourne at Marvel Stadium on Sunday is St Kilda prevailing 98-76.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full betting coverage of the St Kilda vs North Melbourne match on Sunday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so keep checking this article for the latest betting analysis before the St Kilda vs North Melbourne match.

As always, see Stats Insider's Best Bets to get betting tips on every AFL match, as well as predictions for a wide range of other sports.

St Kilda vs North Melbourne: Essential Details

The AFL Round 21 clash between the Saints and Kangaroos at Marvel Stadium is scheduled to start at 1:40pm AEST on Sunday.

• Teams: St Kilda vs North Melbourne
• Date: Sunday 3 August 2025
• Time: 1:40pm AEST
• Venue: Marvel Stadium

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our St Kilda vs North Melbourne predictions are based on 10,000 data-driven simulations of the match, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our AFL tips are trustworthy and reliable, so that you can make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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