Seahawks vs Cardinals Prediction and Preview - NFL Week 10, 2025
Last updated: Nov 3, 2025, 12:00PM | Published: Nov 2, 2025, 4:05AM
The Seattle Seahawks will take on the Arizona Cardinals in NFL Week 10 action at Lumen Field on Monday, beginning at 8:05am AEDT.
This article features Stats Insider's prediction and tips for the Seahawks vs Cardinals game, along with the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Seattle vs Arizona NFL match-up 10,000 times.
Our proven predictive analytics model gives the Seahawks a 56% chance of defeating the Cardinals in Week 10 of the NFL season.
Seahawks vs Cardinals: Odds
The latest Bet365 betting odds in Australia for Monday's NFL game at Lumen Field are shown below:
- Head to Head: Seahawks $1.30, Cardinals $3.65
- Line: Seahawks -7 ($1.91), Cardinals +7 ($1.91)
- Total (Over/Under 44.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Seahawks at $1.30 and the Cardinals at $3.65.
The Seahawks are listed as 7-point favourites against the Cardinals, with odds of $1.91 available at Bet365.
For the underdog Cardinals (+7) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 44.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+7) are predicted to cover the line 88% of the time, while the 44.5-point over/under is expected to go over 53% of the time.
Seahawks vs Cardinals: Best Bets
- Head to Head: Arizona at $3.65 with Bet365
- Line: Cardinals +7 at $1.91 with Bet365
- Total Points: Over 44.5 at $1.91 with Bet365
If you see a 🔥, you know it's one of our best bets of the day across any sport.
Today's Seahawks vs Cardinals predictions are based on market-leading modelling and gambling experience to provide you with the best possible advice every day of the year.
While the Seahawks have a higher chance of winning the game, betting on the Cardinals to win is our preferred option because of the 16.7% edge identified when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges seen on Stats Insider is one of the keys to achieving long-term profitability.
Seahawks vs Cardinals: Prediction
Stats Insider's predicted final score for Seahawks vs Cardinals at Lumen Field in Week 10 is the Seahawks winning 23-21.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Seattle vs Arizona game in Week 10, including data-driven predictions and expert tips.
18+. Odds correct at time of publishing and subject to change.Our model updates frequently, so keep checking this page for the latest betting predictions before the Seattle vs Arizona game.
As always, see Stats Insider's Best Bets to get betting tips on every NFL game, as well as predictions for a wide range of other sports.
Seahawks vs Cardinals: Week 10 Essential Details
The NFL Week 10 game between the Seahawks and Cardinals at Lumen Field is scheduled to start at 8:05am AEDT on Monday.
- Teams: Seattle Seahawks vs Arizona Cardinals
- Date: Monday 10 November 2025
- Time: 8:05am AEDT
- Venue: Lumen Field
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Seattle vs Arizona predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our NFL predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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