Saints vs Patriots Prediction and Preview - NFL Week 6, 2025
Last updated: Oct 10, 2025, 8:02PM | Published: Oct 7, 2025, 12:51AM
The New Orleans Saints will face the New England Patriots in NFL Week 6 action at Caesars Superdome on Monday, starting at 4:00am AEDT.
This article features Stats Insider's prediction and tips for the Saints vs Patriots game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the result of Monday's New Orleans vs New England NFL match-up 10,000 times.
Our independent predictive analytics model gives the Patriots a 61% chance of defeating the Saints in Week 6 of the NFL season.
Saints vs Patriots: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Caesars Superdome are shown here:
- Head to Head: Saints $2.60, Patriots $1.53
- Line: Saints +3.5 ($1.91), Patriots -3.5 ($1.91)
- Total (Over/Under 46 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Saints at $2.60 and the Patriots at $1.53.
The Saints are 3.5-point underdogs against the Patriots, with odds of $1.91 available at Bet365.
For the favourite Patriots (-3.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 46 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Saints (+3.5) are predicted to cover the line 59% of the time, while the 46-point over/under is expected to stay under 51% of the time.
Saints vs Patriots: Best Bets
- Head to Head: New Orleans at $2.60 with Bet365
- Line: Saints +3.5 at $1.91 with Bet365
- Total Points: Under 46 at $1.91 with Bet365
When you see a 🔥, that means you've found one of Stats Insider's best tips for today across all sports.
These Saints vs Patriots betting tips are based on complex simulations and gambling experience to bring you the best possible advice 24/7/365.
While the Patriots have a higher chance of winning the game, betting on the Saints to win is our preferred option due to the edge identified when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen on Stats Insider is crucial to achieving long-term success as a punter.
Saints vs Patriots: Prediction
Stats Insider's predicted final score for Saints vs Patriots at Caesars Superdome in Week 6 is the Patriots winning 24-21.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full betting coverage of the New Orleans vs New England game in Week 6, including data-driven predictions and free betting tips.
18+. Odds correct at time of publishing and subject to change.Saints vs Patriots: TD Scorer Tips
Who will score an anytime touchdown in Saints vs Patriots? The data is in.
According to Stats Insider, New England's Rhamondre Stevenson is the most likely player to score the first touchdown in Saints vs Patriots.
Stevenson has a 9.5% chance of scoring the first TD at Caesars Superdome, while the Patriots RB has a 40.8% chance of scoring an anytime touchdown.
Scroll down for the complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Saints First TD Tips
- Alvin Kamara: 7.4% probability
- Kendre Miller: 6.9% probability
- Chris Olave: 5.9% probability
- Rashid Shaheed: 5.7% probability
- Taysom Hill: 4.9% probability
Patriots First TD Tips
- Rhamondre Stevenson: 9.5% probability
- TreVeyon Henderson: 8.6% probability
- Stefon Diggs: 7.0% probability
- Hunter Henry: 6.5% probability
- Drake Maye: 4.8% probability
Anytime Touchdown Scorer Tips
Saints Anytime TD Tips
- Alvin Kamara: 34.0% probability
- Kendre Miller: 31.9% probability
- Chris Olave: 27.9% probability
- Rashid Shaheed: 27.1% probability
- Taysom Hill: 23.9% probability
Patriots Anytime TD Tips
- Rhamondre Stevenson: 40.8% probability
- TreVeyon Henderson: 38.1% probability
- Stefon Diggs: 32.0% probability
- Hunter Henry: 30.1% probability
- Drake Maye: 23.3% probability
Saints-Patriots Projected Player Stats
Of the starting quarterbacks, the Saints' Spencer Rattler is projected for 219 passing yards. The Patriots' Drake Maye is expected to throw for 234 yards.
Saints Starting QB
- Spencer Rattler: 219 projected passing yards
Patriots Starting QB
- Drake Maye: 234 projected passing yards
Saints Rushing Yards
- Alvin Kamara: 41 projected yards
- Kendre Miller: 35 projected yards
- Spencer Rattler: 21 projected yards
Patriots Rushing Yards
- Rhamondre Stevenson: 44 projected yards
- TreVeyon Henderson: 36 projected yards
- Drake Maye: 26 projected yards
Saints Receiving Yards
- Chris Olave: 64 projected yards
- Rashid Shaheed: 51 projected yards
- Juwan Johnson: 40 projected yards
- Alvin Kamara: 22 projected yards
- Brandin Cooks: 22 projected yards
Patriots Receiving Yards
- Stefon Diggs: 65 projected yards
- Hunter Henry: 43 projected yards
- Kayshon Boutte: 33 projected yards
- TreVeyon Henderson: 20 projected yards
- DeMario Douglas: 19 projected yards
Remember, our model updates regularly, so bookmark this page for the latest betting predictions before the New Orleans vs New England game.
As always, see Stats Insider's Best Bets for the best tips for every NFL game, as well as predictions for a wide range of other sports.
Saints vs Patriots: Week 6 Essential Details
The NFL Week 6 match-up between the Saints and Patriots at Caesars Superdome is scheduled to start at 4:00am AEDT on Monday.
- Teams: New Orleans Saints vs New England Patriots
- Date: Monday 13 October 2025
- Time: 4:00am AEDT
- Venue: Caesars Superdome
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our New Orleans vs New England predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our NFL predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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