Saints vs Panthers Prediction and Preview - NFL Week 15, 2025
Last updated: Dec 14, 2025, 9:25PM | Published: Dec 7, 2025, 5:00AM
The New Orleans Saints will face the Carolina Panthers in NFL Week 15 action at Caesars Superdome on Monday, starting at 8:25am AEDT.
This article features Stats Insider's free betting tips for the Saints vs Panthers game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Monday's New Orleans vs Carolina NFL game 10,000 times.
Our independent predictive analytics model currently gives the Panthers a 59% chance of winning against the Saints in Week 15 of the NFL season.
Saints vs Panthers: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Caesars Superdome are shown here:
- Head to Head: Saints $2.20, Panthers $1.71
- Line: Saints +2.5 ($1.91), Panthers -2.5 ($1.91)
- Total (Over/Under 41.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Saints at $2.20 and the Panthers at $1.71.
The Saints are 2.5-point underdogs against the Panthers, with odds of $1.91 available at Bet365.
For the favourite Panthers (-2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 41.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the bookmakers have got it right and both the Saints and the Panthers have a 50% chance of covering the line.
The 41.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.
Saints vs Panthers: Betting Tips
- Head to Head: Carolina at $1.71 with Bet365
- Line: Panthers -2.5 at $1.91 with Bet365
- Total Points: Under 41.5 at $1.91 with Bet365
Our Saints vs Panthers betting tips are based on detailed simulations and gambling expertise to help you place more informed bets with your chosen online bookie.
Saints vs Panthers: Prediction
Stats Insider's predicted final score for Saints vs Panthers at Caesars Superdome in Week 15 is the Panthers winning 21-19.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the New Orleans vs Carolina game in Week 15, including data-driven predictions and live updatestips.
For in-depth analysis from US experts,, check out Dimers' detailed Saints vs Panthers prediction.
18+. Odds correct at time of publishing and subject to change.Saints vs Panthers: TD Scorer Tips
Who will score the first touchdown in Saints vs Panthers? The latest data is in.
According to Stats Insider, Carolina's Tetairoa McMillan is the most likely player to score the first TD in Saints vs Panthers.
McMillan has a 9.5% chance of scoring the first TD at Caesars Superdome, while the Panthers WR has a 34.8% chance of reaching the end zone at any point in the game.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Saints First TD Tips
- Devin Neal: 8.5% probability
- Chris Olave: 7.5% probability
- Devaughn Vele: 5.7% probability
- Juwan Johnson: 5.3% probability
- Taysom Hill: 4.1% probability
Panthers First TD Tips
- Tetairoa McMillan: 9.5% probability
- Rico Dowdle: 9.0% probability
- Chuba Hubbard: 6.6% probability
- Jalen Coker: 5.1% probability
- Xavier Legette: 5.1% probability
Anytime Touchdown Scorer Tips
Saints Anytime TD Tips
- Devin Neal: 34.6% probability
- Chris Olave: 31.3% probability
- Devaughn Vele: 24.9% probability
- Juwan Johnson: 23.2% probability
- Taysom Hill: 18.3% probability
Panthers Anytime TD Tips
- Tetairoa McMillan: 34.8% probability
- Rico Dowdle: 33.4% probability
- Chuba Hubbard: 25.7% probability
- Jalen Coker: 20.6% probability
- Xavier Legette: 20.5% probability
Saints-Panthers Projected Player Stats
Of the starting quarterbacks, the Saints' Tyler Shough is projected for 216 passing yards, while the Panthers' Bryce Young is expected to throw for 201 yards.
Saints Starting QB
- Tyler Shough: 216 projected passing yards
Panthers Starting QB
- Bryce Young: 201 projected passing yards
Saints Rushing Yards
- Devin Neal: 60 projected yards
- Tyler Shough: 21 projected yards
- Audric Estime: 14 projected yards
Panthers Rushing Yards
- Rico Dowdle: 57 projected yards
- Chuba Hubbard: 47 projected yards
- Bryce Young: 12 projected yards
Saints Receiving Yards
- Chris Olave: 66 projected yards
- Devaughn Vele: 41 projected yards
- Juwan Johnson: 41 projected yards
- Mason Tipton: 22 projected yards
- Devin Neal: 19 projected yards
Panthers Receiving Yards
- Tetairoa McMillan: 62 projected yards
- Jalen Coker: 39 projected yards
- Xavier Legette: 27 projected yards
- Ja'Tavion Sanders: 18 projected yards
- Chuba Hubbard: 15 projected yards
Remember, our model updates frequently, so bookmark this page for the latest betting analysis before the New Orleans vs Carolina game.
As always, see our Best Bets for betting tips on every NFL game, plus predictions for a wide range of other sports.
Saints vs Panthers: Week 15 Essential Details
The NFL Week 15 match-up between the Saints and Panthers at Caesars Superdome is scheduled to commence at 8:25am AEDT on Monday.
- Teams: New Orleans Saints vs Carolina Panthers
- Date: Monday 15 December 2025
- Time: 8:25am AEDT
- Venue: Caesars Superdome
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our New Orleans vs Carolina predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our NFL predictions for betting purposes, it's important to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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