Reds vs Pirates Prediction and MLB Tips - 25 September 2025
Last updated: Sep 24, 2025, 10:36PM | Published: Sep 23, 2025, 7:31PM
The Cincinnati Reds will sqaure off with the Pittsburgh Pirates in Game of the League Series at Great American Ball Park on Thursday, beginning at 8:40am AEST.
The Reds will send Hunter Greene (7-4, 2.74 ERA) to the mound, while the Pirates are going with Paul Skenes (10-10, 2.03 ERA).
This article features Stats Insider's free betting tips for the Reds vs Pirates game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the outcome of Thursday's Cincinnati vs Pittsburgh MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Reds a 53% chance of winning against the Pirates at Great American Ball Park.
Reds vs Pirates: Odds
The latest betting odds in Australia for Thursday's MLB game at Great American Ball Park are listed below:
- Head to Head: Reds $1.77, Pirates $2.10
- Line: Reds -1.5 ($2.75), Pirates +1.5 ($1.48)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $1.77 and the Pirates at $2.10.
The Reds are 1.5-run favourites against the Pirates, with odds of $2.75 available at TAB.
For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.48.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Pirates (+1.5) are predicted to cover the line 66% of the time, while the 7-run over/under is expected to go over 52% of the time.
Reds vs Pirates: Best Bets
- Head to Head: Pittsburgh at $2.10 with TAB
- Line: Pirates +1.5 at $1.48 with TAB
- Total Runs: Over 7 at $1.91 with TAB
Today's Reds vs Pirates best bets are based on complex simulations and wagering experience to help you place more informed bets with your chosen online bookie.
While the Reds have a higher chance of winning the game, betting on the Pirates to win is our recommended option due to the 1.1% edge identified when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges seen here at Stats Insider is crucial to being a profitable punter in the long run.
Reds vs Pirates: Prediction
Stats Insider provides full betting coverage of the Cincinnati vs Pittsburgh game on Thursday, including data-driven predictions and the best betting tips.
Our model updates frequently, so keep checking this article for the latest betting tips before the Cincinnati vs Pittsburgh game.
As always, see our Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.
Reds vs Pirates: Essential Details
The match-up between the Reds and Pirates at Great American Ball Park is scheduled to start at 8:40am AEST on Thursday.
- Teams: Cincinnati Reds vs Pittsburgh Pirates
- Date: Thursday 25 September 2025
- Time: 8:40am AEST
- Venue: Great American Ball Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cincinnati vs Pittsburgh predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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