Reds vs Pirates Prediction and MLB Tips - 24 September 2025
Last updated: Sep 23, 2025, 10:43PM | Published: Sep 22, 2025, 6:28PM
The Cincinnati Reds will face the Pittsburgh Pirates in Game of the League Series at Great American Ball Park on Wednesday, commencing at 8:40am AEST.
The Reds will have Brady Singer (14-10, 3.86 ERA) start, while the Pirates are going with Johan Oviedo (2-0, 3.52 ERA).
This article features Stats Insider's top betting tips for the Reds vs Pirates game, plus the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Wednesday's Cincinnati vs Pittsburgh MLB game 10,000 times.
Our independent predictive analytics model gives the Reds a 59% chance of winning against the Pirates at Great American Ball Park.
Reds vs Pirates: Odds
The latest betting odds in Australia for Wednesday's MLB game at Great American Ball Park are listed below:
- Head to Head: Reds $1.59, Pirates $2.45
- Line: Reds -1.5 ($2.25), Pirates +1.5 ($1.67)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $1.59 and the Pirates at $2.45.
The Reds are 1.5-run favourites against the Pirates, with odds of $2.25 available at TAB.
For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.67.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Pirates (+1.5) are predicted to cover the line 60% of the time, while the 8-run over/under is expected to go over 52% of the time.
Reds vs Pirates: Best Bets
- Head to Head: Pittsburgh at $2.45 with TAB
- Line: Pirates +1.5 at $1.67 with TAB
- Total Runs: Over 8 at $1.91 with TAB
Stats Insider's Reds vs Pirates predictions are based on complex simulations and wagering experience to provide you with the best possible advice around the clock.
While the Reds have a higher chance of winning the game, betting on the Pirates to win is our recommended option because of the 1.8% edge identified when comparing our data-driven probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is one of the keys to achieving long-term success as a sports bettor.
Reds vs Pirates: Prediction
Stats Insider provides full coverage of the Cincinnati vs Pittsburgh game on Wednesday, including data-driven predictions and the best betting tips.
Our model updates regularly, so bookmark this article for the latest betting predictions before the Cincinnati vs Pittsburgh game.
As always, see our Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.
Reds vs Pirates: Essential Details
The game between the Reds and Pirates at Great American Ball Park is scheduled to start at 8:40am AEST on Wednesday.
- Teams: Cincinnati Reds vs Pittsburgh Pirates
- Date: Wednesday 24 September 2025
- Time: 8:40am AEST
- Venue: Great American Ball Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cincinnati vs Pittsburgh predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you decide to use our predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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