Reds vs Cubs Prediction and MLB Tips - 20 September 2026
Last updated: Sep 18, 2026, 9:36PM | Published: Sep 18, 2026, 6:28PM
The Cincinnati Reds will take on the Chicago Cubs in MLB action at Great American Ball Park on Sunday, starting at 8:40am AEST.
The Reds will send Nick Lodolo (3-5, 5.12 ERA) to the mound, pitting him against Matthew Boyd (8-5, 4.16 ERA) for the Cubs.
This article features Stats Insider's prediction and tips for the Reds vs Cubs game, as well as the latest betting odds in Australia.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the outcome of Sunday's Cincinnati vs Cubs MLB match-up 10,000 times.
Our independent predictive analytics model gives the Cubs a 54% chance of beating the Reds at Great American Ball Park.
Reds vs Cubs: Odds
The current betting odds in Australia for Sunday's MLB game at Great American Ball Park are shown here:
- Head to Head: Reds $2.20, Cubs $1.71
- Line: Reds +1.5 ($1.72), Cubs -1.5 ($2.20)
- Total (Over/Under 9.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $2.20 and the Cubs at $1.71.
The Reds are listed as 1.5-run underdogs against the Cubs, with odds of $1.72 available at TAB.
For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.20.
The over/under for total runs scored is set at 9.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Reds (+1.5) are predicted to cover the line 58% of the time, while the 9.5-run over/under is expected to go over 51% of the time.
Reds vs Cubs: Best Bets
- Head to Head: Cincinnati at $2.20 with TAB
- Line: Reds +1.5 at $1.72 with TAB
- Total Runs: Over 9.5 at $1.91 with TAB
Our Reds vs Cubs best bets are based on detailed modelling and gambling experience to help you place more informed bets with your chosen online bookie.
While the Cubs have a higher chance of winning the game, betting on the Reds to win is our recommended option because of the 1.9% edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges published here at Stats Insider is pivotal to achieving long-term profitability.
Reds vs Cubs: Prediction
Stats Insider provides full betting coverage of the Cincinnati vs Cubs game on Sunday, including data-driven predictions and the best betting tips.
Remember, our model updates regularly, so keep checking this article for the latest betting predictions before the Cincinnati vs Cubs game.
As always, see our Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.
Reds vs Cubs: Essential Details
The match-up between the Reds and Cubs at Great American Ball Park is scheduled to begin at 8:40am AEST on Sunday.
- Teams: Cincinnati Reds vs Chicago Cubs
- Date: Sunday 20 September 2026
- Time: 8:40am AEST
- Venue: Great American Ball Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Cincinnati vs Cubs predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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