Reds vs Cardinals Prediction and MLB Tips - 25 May 2026
Last updated: May 24, 2026, 4:50PM | Published: May 23, 2026, 6:41PM
The Cincinnati Reds will sqaure off with the St. Louis Cardinals in MLB action at Great American Ball Park on Monday, beginning at 3:40am AEST.
The Reds will send Brady Singer (2-4, 6.26 ERA) to the mound, pitting him against Brycen Mautz (0-0, 0.00 ERA) for the Cardinals.
This article features Stats Insider's top betting tips for the Reds vs Cardinals game, as well as the latest betting odds in Australia.
Who Will Win?
Utilising trusted machine learning and data, Stats Insider has simulated the result of Monday's Cincinnati vs St. Louis MLB game 10,000 times.
Our proven predictive analytics model gives the Reds a 53% chance of winning against the Cardinals at Great American Ball Park.
Reds vs Cardinals: Odds
The current betting odds in Australia for Monday's MLB game at Great American Ball Park are shown below:
- Head to Head: Reds $1.83, Cardinals $2.00
- Line: Reds -1.5 ($2.60), Cardinals +1.5 ($1.53)
- Total (Over/Under 10 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $1.83 and the Cardinals at $2.00.
The Reds are 1.5-run favourites against the Cardinals, with odds of $2.60 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.53.
The over/under for total runs scored is set at 10 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 10-run over/under is expected to stay under 51% of the time.
Reds vs Cardinals: Betting Tips
- Head to Head: Cincinnati at $1.83 with TAB
- Line: Reds -1.5 at $2.60 with TAB
- Total Runs: Under 10 at $1.91 with TAB
Stats Insider's Reds vs Cardinals predictions are based on detailed simulations and gambling intelligence to help you place better bets with your chosen online bookie.
Although the Cardinals are more likely to cover the line, our best bet of Reds -1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the best odds available.
Reds vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Cincinnati vs St. Louis game on Monday, including data-driven predictions and expert tips.
Our model updates frequently, so refresh this page for the latest betting tips before the Cincinnati vs St. Louis match-up.
As always, see Stats Insider's Best Bets for the best tips on every MLB game, plus predictions for a wide range of other sports.
Reds vs Cardinals: Essential Details
The match-up between the Reds and Cardinals at Great American Ball Park is scheduled to commence at 3:40am AEST on Monday.
- Teams: Cincinnati Reds vs St. Louis Cardinals
- Date: Monday 25 May 2026
- Time: 3:40am AEST
- Venue: Great American Ball Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Cincinnati vs St. Louis predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.
