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Reds vs Cardinals Prediction and MLB Tips - 1 September 2025

The Cincinnati Reds will take on the St. Louis Cardinals in MLB action at Great American Ball Park on Monday, beginning at 2:10am AEST.

The Reds will have Brady Singer (11-9, 4.06 ERA) start, up against Andre Pallante (6-12, 5.44 ERA) for the Cardinals.

This article features Stats Insider's free betting tips for the Reds vs Cardinals game, plus the latest betting odds in Australia.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the result of Monday's Cincinnati vs St. Louis MLB game 10,000 times.

Our leading predictive analytics model currently gives the Reds a 56% chance of beating the Cardinals at Great American Ball Park.

Reds vs Cardinals: Odds

The latest betting odds in Australia for Monday's MLB game at Great American Ball Park are listed here:

  • Head to Head: Reds $1.67, Cardinals $2.25
  • Line: Reds -1.5 ($2.40), Cardinals +1.5 ($1.61)
  • Total (Over/Under 8 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Reds at $1.67 and the Cardinals at $2.25.

The Reds are listed as 1.5-run favourites against the Cardinals, with odds of $2.40 available at TAB.

For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.61.

The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 62% of the time, while the 8-run over/under is expected to go over 51% of the time.

Reds vs Cardinals: Betting Tips

  • Head to Head: St. Louis at $2.25 with TAB
  • Line: Cardinals +1.5 at $1.61 with TAB
  • Total Runs: Under 8 at $1.91 with TAB

These Reds vs Cardinals best bets are based on detailed simulations and betting expertise to bring you the best possible advice around the clock.

While the Reds have a higher chance of winning the game, betting on the Cardinals to win is our recommended option due to the 1.7% edge found when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges published on Stats Insider is crucial to being profitable in the long run.

Furthermore, despite the Over being more likely to hit in this game, Under 8 is our best bet because of the better odds ($1.91) that are available from TAB.

Reds vs Cardinals: Prediction

Stats Insider provides full betting coverage of the Cincinnati vs St. Louis game on Monday, including data-driven predictions and live win probabilitiestips.

Our model updates regularly, so bookmark this article for the latest betting analysis before the Cincinnati vs St. Louis match-up.

As always, see Stats Insider's Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.

Reds vs Cardinals: Essential Details

The match-up between the Reds and Cardinals at Great American Ball Park is scheduled to begin at 2:10am AEST on Monday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Cincinnati vs St. Louis predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.

If you decide to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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