Red Sox vs Orioles Prediction and MLB Tips - 22 July 2026
Last updated: Jul 21, 2026, 10:21PM | Published: Jul 21, 2026, 3:30AM
The Boston Red Sox will take on the Baltimore Orioles in MLB action at Fenway Park on Wednesday, starting at 9:10am AEST.
The Red Sox will have Eduardo Rivera (0-0, 2.89 ERA) start, while the Orioles are going with Kyle Bradish (6-9, 3.61 ERA).
This article features Stats Insider's prediction and tips for the Red Sox vs Orioles game, as well as the latest betting odds in Australia.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Wednesday's Boston vs Baltimore MLB match-up 10,000 times.
Our leading predictive analytics model is unable to split the two teams, giving both the Red Sox and the Orioles an equal 50% chance of winning the game.
Red Sox vs Orioles: Odds
The latest betting odds in Australia for Wednesday's MLB game at Fenway Park are shown below:
- Head to Head: Red Sox $1.87, Orioles $1.95
- Line: Red Sox -1.5 ($2.75), Orioles +1.5 ($1.48)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Red Sox at $1.87 and the Orioles at $1.95.
The Red Sox are listed as 1.5-run favourites against the Orioles, with odds of $2.75 available at TAB.
For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.48.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Orioles (+1.5) are predicted to cover the line 65% of the time, while the 8.5-run over/under is expected to go over 59% of the time.
Red Sox vs Orioles: Best Bets
- Head to Head: Baltimore at $1.95 with TAB
- Line: Orioles +1.5 at $1.48 with TAB
- Total Runs: Over 8.5 at $1.91 with TAB
Our Red Sox vs Orioles betting tips are based on detailed modelling and betting intelligence to help you place smarter bets with your chosen online bookie.
Red Sox vs Orioles: Prediction
Stats Insider provides full coverage of the Boston vs Baltimore game on Wednesday, including data-driven predictions and expert tips.
Our model updates regularly, so refresh this page for the latest betting predictions before the Boston vs Baltimore game.
As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.
Red Sox vs Orioles: Essential Details
The game between the Red Sox and Orioles at Fenway Park is scheduled to commence at 9:10am AEST on Wednesday.
- Teams: Boston Red Sox vs Baltimore Orioles
- Date: Wednesday 22 July 2026
- Time: 9:10am AEST
- Venue: Fenway Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Boston vs Baltimore predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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