Red Sox vs Guardians Prediction and MLB Tips - 3 September 2025
Last updated: Sep 2, 2025, 7:06PM | Published: Sep 1, 2025, 6:32PM
The Boston Red Sox will take on the Cleveland Guardians in MLB action at Fenway Park on Wednesday, beginning at 8:45am AEST.
Garrett Crochet (14-5, 2.40 ERA) will start for the Red Sox, while the Guardians will counter with Slade Cecconi (5-6, 4.41 ERA).
This article features Stats Insider's top betting tips for the Red Sox vs Guardians game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the outcome of Wednesday's Boston vs Cleveland MLB game 10,000 times.
Our proven predictive analytics model currently gives the Red Sox a 70% chance of defeating the Guardians at Fenway Park.
Red Sox vs Guardians: Odds
The latest betting odds in Australia for Wednesday's MLB game at Fenway Park are listed here:
- Head to Head: Red Sox $1.38, Guardians $3.14
- Line: Red Sox -1.5 ($1.82), Guardians +1.5 ($2.02)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Red Sox at $1.38 and the Guardians at $3.14.
The Red Sox are listed as 1.5-run favourites against the Guardians, with odds of $1.82 available at TAB.
For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $2.02.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Red Sox (-1.5) are predicted to cover the line 52% of the time, while the 7.5-run over/under is expected to go over 52% of the time.
Red Sox vs Guardians: Betting Tips
- Head to Head: Boston at $1.38 with TAB
- Line: Guardians +1.5 at $2.02 with TAB
- Total Runs: Over 7.5 at $1.91 with TAB
Today's Red Sox vs Guardians best bets are based on world-class modelling and gambling expertise to provide you with the best possible advice 24/7/365.
Even though the Red Sox are more likely to cover the line, our best bet of Guardians +1.5 is based on the likelihood of that happening, as projected by our predictive analytics model, and the best odds available.
Red Sox vs Guardians: Prediction
Stats Insider provides full betting coverage of the Boston vs Cleveland game on Wednesday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates regularly, so keep checking this page for the latest betting predictions before the Boston vs Cleveland match-up.
As always, see Stats Insider's Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.
Red Sox vs Guardians: Essential Details
The match-up between the Red Sox and Guardians at Fenway Park is scheduled to begin at 8:45am AEST on Wednesday.
- Teams: Boston Red Sox vs Cleveland Guardians
- Date: Wednesday 3 September 2025
- Time: 8:45am AEST
- Venue: Fenway Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Boston vs Cleveland predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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