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Real Madrid vs Espanyol Prediction and Tips - 21 September 2025

Real Madrid will take on Espanyol in La Liga action at Estadio Santiago Bernabéu on Sunday, starting at 12:15am AEST.

This article features Stats Insider's best betting tips for the Real Madrid vs Espanyol game, along with the latest betting odds in Australia.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the result of Sunday's Real Madrid vs Espanyol La Liga match 10,000 times.

Our leading predictive analytics model currently gives Real Madrid a 74.3% chance of winning, Espanyol a 10.2% chance of winning, and the draw a 15.4% chance of occurring.

Real Madrid vs Espanyol: Odds

The latest Bet365 betting odds in Australia for Sunday's La Liga clash at Estadio Santiago Bernabéu are shown here:

  • Head to Head: Real Madrid $1.20, Espanyol $13.00, Draw $7.00
  • Total (Over/Under 2.5 Goals): Over $1.40, Under $3.00

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has Real Madrid at $1.20 and Espanyol at $13.00.

Lastly, Bet365 currently has odds of $7.00 for a draw if you believe the score will be level after 90 minutes.

The over/under for total goals scored is set at 2.5 with Bet365, which has odds of $1.40 for the over and $3.00 for the under.

Real Madrid vs Espanyol: Betting Tips

  • Head to Head: Espanyol at $13.00 with Bet365
  • Total Goals: Under 2.5 at $3.00 with Bet365

Stats Insider's Real Madrid vs Espanyol predictions are based on complex simulations and betting expertise to help you place more informed bets with your chosen online bookie.

Betting on Espanyol to win is the best option due to the 2.5% edge identified when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges seen on Stats Insider is pivotal to being profitable in the long run.

Despite the Over being more likely to hit in this game, Under 2.5 is our best bet because of the better odds ($3.00) that are available from Bet365.

Real Madrid vs Espanyol: Prediction

Stats Insider provides full coverage of the Real Madrid vs Espanyol match on Sunday, including data-driven predictions and top betting tips.

18+. Odds correct at time of publishing and subject to change.

Remember, our model updates regularly, so keep checking this article for the latest betting predictions before the Real Madrid vs Espanyol match.

As always, see Stats Insider's Best Bets for betting tips on every La Liga match, as well as predictions for a wide range of other sports.

Real Madrid vs Espanyol: Essential Details

The La Liga game between Real Madrid and Espanyol at Estadio Santiago Bernabéu is scheduled to begin at 12:15am AEST on Sunday.

  • Teams: Real Madrid vs Espanyol
  • Date: Sunday 21 September 2025
  • Time: 12:15am AEST
  • Venue: Estadio Santiago Bernabéu (Madrid)

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Real Madrid vs Espanyol predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our La Liga tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on La Liga

Stats Insider is your go-to source for betting on the La Liga in Australia, with the latest La Liga betting news, predictions for every La Liga game, and futures odds for the La Liga.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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