Real Madrid vs Espanyol Prediction and Tips - 21 September 2025
Last updated: Sep 20, 2025, 2:06PM | Published: Sep 18, 2025, 12:36PM
Real Madrid will face Espanyol in La Liga action at Estadio Santiago Bernabéu on Sunday, starting at 12:15am AEST.
This article features Stats Insider's top betting tips for the Real Madrid vs Espanyol game, as well as the latest betting odds in Australia.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the outcome of Sunday's Real Madrid vs Espanyol La Liga match 10,000 times.
Our independent predictive analytics model gives Real Madrid a 74.3% chance of winning, Espanyol a 10.2% chance of winning, and the draw a 15.4% chance of happening.
Real Madrid vs Espanyol: Odds
The current Bet365 betting odds in Australia for Sunday's La Liga clash at Estadio Santiago Bernabéu are shown here:
- Head to Head: Real Madrid $1.18, Espanyol $15.00, Draw $7.00
- Total (Over/Under 2.5 Goals): Over $1.40, Under $3.00
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has Real Madrid at $1.18 and Espanyol at $15.00.
Lastly, Bet365 has odds of $7.00 for a draw if you believe both sides will be even after 90 minutes.
The over/under for total goals scored is set at 2.5 with Bet365, which has odds of $1.40 for the over and $3.00 for the under.
Real Madrid vs Espanyol: Betting Tips
Today's Real Madrid vs Espanyol best bets are based on market-leading simulations and gambling expertise to give you the best possible advice every day of the year.
Betting on Espanyol to win is the best option because of the 3.6% edge found when comparing our data-led probabilities to the sportsbooks' odds.
Taking advantage of the edges seen on Stats Insider is crucial to achieving long-term profitability when punting on sports.
Despite the Over being more likely to hit in this game, Under 2.5 is our best bet because of the better odds ($3.00) that are available from Bet365.
Real Madrid vs Espanyol: Prediction
Stats Insider provides full coverage of the Real Madrid vs Espanyol match on Sunday, including data-driven predictions and expert tips.
18+. Odds correct at time of publishing and subject to change.Remember, our model updates frequently, so keep checking this page for the latest betting tips before the Real Madrid vs Espanyol match.
As always, see our Best Bets to get betting tips for every La Liga match, plus predictions for a wide range of other sports.
Real Madrid vs Espanyol: Essential Details
The La Liga game between Real Madrid and Espanyol at Estadio Santiago Bernabéu is scheduled to begin at 12:15am AEST on Sunday.
- Teams: Real Madrid vs Espanyol
- Date: Sunday 21 September 2025
- Time: 12:15am AEST
- Venue: Estadio Santiago Bernabéu (Madrid)
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Real Madrid vs Espanyol predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our La Liga tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on La Liga
Stats Insider is your home for betting on the La Liga in Australia, with the latest La Liga betting news, predictions for every La Liga game, and futures odds for the La Liga.

