Rays vs Red Sox Prediction and MLB Tips - 21 September 2025
Last updated: Sep 20, 2025, 11:06PM | Published: Sep 19, 2025, 6:30PM
The Tampa Bay Rays will face the Boston Red Sox in Game of the League Series at George M. Steinbrenner Field on Sunday, commencing at 9:05am AEST.
The Rays will send Adrian Houser (8-4, 3.11 ERA) to the mound, up against Kyle Harrison (1-1, 4.05 ERA) for the Red Sox.
This article features Stats Insider's top betting tips for the Rays vs Red Sox game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the result of Sunday's Tampa Bay vs Boston MLB game 10,000 times.
Our proven predictive analytics model currently gives the Red Sox a 52% chance of winning against the Rays at George M. Steinbrenner Field.
Rays vs Red Sox: Odds
The current betting odds in Australia for Sunday's MLB game at George M. Steinbrenner Field are shown here:
- Head to Head: Rays $1.91, Red Sox $1.91
- Line: Rays +1.5 ($1.54), Red Sox -1.5 ($2.54)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Rays at $1.91 and the Red Sox at $1.91.
The Rays are 1.5-run underdogs against the Red Sox, with odds of $1.54 available at TAB.
For the favourite Red Sox (-1.5) to cover the line, TAB offers odds of $2.54.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Rays (+1.5) are predicted to cover the line 61% of the time, while the 8-run over/under is expected to go over 51% of the time.
Rays vs Red Sox: Best Bets
- Head to Head: Boston at $1.91 with TAB
- Line: Red Sox -1.5 at $2.54 with TAB
- Total Runs: Over 8 at $1.91 with TAB
Stats Insider's Rays vs Red Sox predictions are based on market-leading modelling and gambling experience to provide you with the best possible advice 24/7/365.
Although the Rays are more likely to cover the line, our best bet of Red Sox -1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the top odds available.
Rays vs Red Sox: Prediction
Stats Insider provides full coverage of the Tampa Bay vs Boston game on Sunday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so keep checking this page for the latest betting tips before the Tampa Bay vs Boston match-up.
As always, see Stats Insider's Best Bets for betting tips on every MLB game, plus predictions for a wide range of other sports.
Rays vs Red Sox: Essential Details
The game between the Rays and Red Sox at George M. Steinbrenner Field is scheduled to begin at 9:05am AEST on Sunday.
- Teams: Tampa Bay Rays vs Boston Red Sox
- Date: Sunday 21 September 2025
- Time: 9:05am AEST
- Venue: George M. Steinbrenner Field
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Tampa Bay vs Boston predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.