Rays vs Cardinals Prediction and MLB Tips - 22 August 2025
Last updated: Aug 21, 2025, 11:35PM | Published: Aug 20, 2025, 8:43PM
The Tampa Bay Rays will sqaure off with the St. Louis Cardinals in MLB action at George M. Steinbrenner Field on Friday, beginning at 9:35am AEST.
Joe Boyle (1-2, 4.68 ERA) will start on the mound for the Rays, while the Cardinals will counter with Sonny Gray (11-6, 4.30 ERA).
This article features Stats Insider's top betting tips for the Rays vs Cardinals game, as well as the latest betting odds in Australia.
Who Will Win?
Utilising trusted machine learning and data, Stats Insider has simulated the outcome of Friday's Tampa Bay vs St. Louis MLB match-up 10,000 times.
Our leading predictive analytics model is currently unable to split the two teams, giving both the Rays and the Cardinals an equal 50% chance of winning the game.
Rays vs Cardinals: Odds
The latest betting odds in Australia for Friday's MLB game at George M. Steinbrenner Field are listed below:
- Head to Head: Rays $2.00, Cardinals $1.83
- Line: Rays +1.5 ($1.59), Cardinals -1.5 ($2.45)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Rays at $2.00 and the Cardinals at $1.83.
The Rays are listed as 1.5-run underdogs against the Cardinals, with odds of $1.59 available at TAB.
For the favourite Cardinals (-1.5) to cover the line, TAB offers odds of $2.45.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Rays (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to stay under 57% of the time.
Rays vs Cardinals: Best Bets
- Head to Head: Tampa Bay at $2.00 with TAB
- Line: Rays +1.5 at $1.59 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Today's Rays vs Cardinals predictions are based on detailed simulations and wagering expertise to help you place better bets with your chosen online bookie.
Rays vs Cardinals: Prediction
Stats Insider provides full coverage of the Tampa Bay vs St. Louis game on Friday, including data-driven predictions and free betting tips.
Remember, our model updates regularly, so refresh this page for the latest betting analysis before the Tampa Bay vs St. Louis game.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Rays vs Cardinals: Essential Details
The game between the Rays and Cardinals at George M. Steinbrenner Field is scheduled to start at 9:35am AEST on Friday.
- Teams: Tampa Bay Rays vs St. Louis Cardinals
- Date: Friday 22 August 2025
- Time: 9:35am AEST
- Venue: George M. Steinbrenner Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Tampa Bay vs St. Louis predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.