Rays vs Astros Prediction and MLB Tips - 21 May 2025
Last updated: May 20, 2025, 11:05PM | Published: May 20, 2025, 4:29AM
The Tampa Bay Rays will face the Houston Astros in MLB action at George M. Steinbrenner Field on Wednesday, beginning at 9:05am AEST.
The Rays will have Zack Littell (3-5, 4.31 ERA) start, up against Brandon Walter (0-0, 0.00 ERA) for the Astros.
This article features Stats Insider's free betting tips for the Rays vs Astros game, along with the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the result of Wednesday's Tampa Bay vs Houston MLB game 10,000 times.
Our proven predictive analytics model gives the Rays a 53% chance of beating the Astros at George M. Steinbrenner Field.
Rays vs Astros: Odds
The current betting odds in Australia for Wednesday's MLB game at George M. Steinbrenner Field are listed below:
- Head to Head: Rays $1.71, Astros $2.20
- Line: Rays -1.5 ($2.50), Astros +1.5 ($1.56)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Rays at $1.71 and the Astros at $2.20.
The Rays are listed as 1.5-run favourites against the Astros, with odds of $2.50 available at TAB.
For the underdog Astros (+1.5) to cover the line, TAB offers odds of $1.56.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Astros (+1.5) are predicted to cover the line 66% of the time, while the 9-run over/under is expected to stay under 55% of the time.
Rays vs Astros: Betting Tips
- Head to Head: Houston at $2.20 with TAB
- Line: Astros +1.5 at $1.56 with TAB
- Total Runs: Under 9 at $1.91 with TAB
When you see a 🔥, you know it's one of our best tips of the day across all sports.
Today's Rays vs Astros best bets are based on detailed modelling and wagering intelligence to help you place better bets with your chosen online bookie.
While the Rays have a higher chance of winning the game, betting on the Astros to win is our preferred option due to the 3.4% edge identified when comparing our data-driven probabilities to the odds currently available.
Taking advantage of the edges seen on Stats Insider is pivotal to achieving long-term profitability.
Rays vs Astros: Prediction
Stats Insider provides full betting coverage of the Tampa Bay vs Houston game on Wednesday, including data-driven predictions and computer tips.
Our model updates frequently, so bookmark this page for the latest betting tips before the Tampa Bay vs Houston game.
As always, see our Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.
Rays vs Astros: Essential Details
The game between the Rays and Astros at George M. Steinbrenner Field is scheduled to commence at 9:05am AEST on Wednesday.
- Teams: Tampa Bay Rays vs Houston Astros
- Date: Wednesday 21 May 2025
- Time: 9:05am AEST
- Venue: George M. Steinbrenner Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Tampa Bay vs Houston predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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