Rams vs Lions Prediction and Preview - NFL Week 15, 2025

The Los Angeles Rams will take on the Detroit Lions in NFL Week 15 action at SoFi Stadium on Monday, December 15, commencing at 8:25am AEDT.

This article features Stats Insider's prediction and tips for the Rams vs Lions game, along with the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the outcome of Lions vs Rams 10,000 times.

Our proven predictive analytics model currently gives the Rams a 66% chance of winning against the Lions at SoFi Stadium.

Rams vs Lions: Odds

The latest Bet365 betting odds in Australia for this NFL game at SoFi Stadium are shown below:

• Head to Head: Rams $1.48, Lions $2.75
• Line: Rams -4.5 ($1.91), Lions +4.5 ($1.91)
• Total (Over/Under 51.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Rams at $1.48 and the Lions at $2.75.

The Rams are listed as 4.5-point favourites against the Lions, with odds of $1.91 available at Bet365.

For the underdog Lions (+4.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 51.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the bookmakers have got it right and both the Rams and the Lions have a 50% chance of covering the line.

The 51.5-point over/under is expected to stay under 54% of the time.

Rams vs Lions: Betting Tips

• Head to Head: Detroit at $2.75 with Bet365
• Line: Lions +4.5 at $1.91 with Bet365
• Total Points: Under 51.5 at $1.91 with Bet365

Stats Insider's Rams vs Lions betting tips are based on complex simulations and wagering intelligence to provide you with the best possible advice every day of the year.

While the Rams have a higher chance of winning the game, betting on the Lions to win is our preferred option due to the edge identified when comparing our data-led probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is one of the keys to being profitable in the long run.

Rams vs Lions: Prediction

Stats Insider's predicted final score for Rams vs Lions at SoFi Stadium in Week 15 is the Rams winning 27-22.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the LA Rams vs Detroit game in Week 15, including data-driven predictions and free tips.

Remember, our model updates frequently, so keep checking this page for the latest betting predictions before the LA Rams vs Detroit match-up.

As always, see Stats Insider's Best Bets for the best tips on every NFL game, as well as predictions for a wide range of other sports.

Rams vs Lions: Week 15 Essential Details

The NFL Week 15 match-up between the Rams and Lions at SoFi Stadium is scheduled to begin at 8:25am AEDT on Monday, December 15.

• Teams: Los Angeles Rams vs Detroit Lions
• Date: Monday 15 December 2025
• Time: 8:25am AEDT
• Venue: SoFi Stadium

All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our LA Rams vs Detroit predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our NFL predictions for betting purposes, it's important to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on NFL

Stats Insider is your home for betting on the NFL in Australia, with the latest NFL betting news, predictions for every NFL game, and Super Bowl odds for the NFL.