Pirates vs White Sox Prediction and MLB Tips - 21 July 2025
Last updated: Jul 20, 2025, 5:35PM | Published: Jul 19, 2025, 7:47PM
The Pittsburgh Pirates will take on the Chicago White Sox in MLB action at PNC Park on Monday, commencing at 3:35am AEST.
The Pirates will send Andrew Heaney (4-8, 4.59 ERA) to the mound, pitting him against Aaron Civale (1-6, 5.30 ERA) for the White Sox.
This article features Stats Insider's prediction and tips for the Pirates vs White Sox game, along with the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the outcome of Monday's Pittsburgh vs White Sox MLB game 10,000 times.
Our proven predictive analytics model gives the Pirates a 59% chance of defeating the White Sox at PNC Park.
Pirates vs White Sox: Odds
The latest betting odds in Australia for Monday's MLB game at PNC Park are listed here:
- Head to Head: Pirates $1.67, White Sox $2.25
- Line: Pirates -1.5 ($2.45), White Sox +1.5 ($1.59)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.67 and the White Sox at $2.25.
The Pirates are listed as 1.5-run favourites against the White Sox, with odds of $2.45 available at TAB.
For the underdog White Sox (+1.5) to cover the line, TAB offers odds of $1.59.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the White Sox (+1.5) are predicted to cover the line 60% of the time, while the 9-run over/under is expected to stay under 55% of the time.
Pirates vs White Sox: Best Bets
- Head to Head: Pittsburgh at $1.67 with TAB
- Line: Pirates -1.5 at $2.45 with TAB
- Total Runs: Under 9 at $1.91 with TAB
These Pirates vs White Sox betting tips are based on world-class modelling and gambling experience to give you the best possible advice 24/7/365.
Although the White Sox are more likely to cover the line, our best bet of Pirates -1.5 is based on the chance of that happening, as projected by our predictive analytics model, and the top odds available.
Pirates vs White Sox: Prediction
Stats Insider provides full coverage of the Pittsburgh vs White Sox game on Monday, including data-driven predictions and expert tips.
Our model updates frequently, so keep checking this article for the latest betting analysis before the Pittsburgh vs White Sox match-up.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.
Pirates vs White Sox: Essential Details
The match-up between the Pirates and White Sox at PNC Park is scheduled to start at 3:35am AEST on Monday.
- Teams: Pittsburgh Pirates vs Chicago White Sox
- Date: Monday 21 July 2025
- Time: 3:35am AEST
- Venue: PNC Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Pittsburgh vs White Sox predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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