Pirates vs Reds Prediction and MLB Tips - 21 May 2025
Last updated: May 20, 2025, 10:41PM | Published: May 19, 2025, 6:29PM
The Pittsburgh Pirates will take on the Cincinnati Reds in MLB action at PNC Park on Wednesday, starting at 8:40am AEST.
Bailey Falter (2-3, 4.02 ERA) will get the ball for the Pirates, while the Reds are going with Nick Martinez (2-4, 3.66 ERA).
This article features Stats Insider's prediction and tips for the Pirates vs Reds game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the result of Wednesday's Pittsburgh vs Cincinnati MLB game 10,000 times.
Our proven predictive analytics model currently gives the Reds a 55% chance of beating the Pirates at PNC Park.
Pirates vs Reds: Odds
The current betting odds in Australia for Wednesday's MLB game at PNC Park are listed here:
- Head to Head: Pirates $2.25, Reds $1.67
- Line: Pirates +1.5 ($1.72), Reds -1.5 ($2.20)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $2.25 and the Reds at $1.67.
The Pirates are listed as 1.5-run underdogs against the Reds, with odds of $1.72 available at TAB.
For the favourite Reds (-1.5) to cover the line, TAB offers odds of $2.20.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Pirates (+1.5) are predicted to cover the line 60% of the time, while the 8-run over/under is expected to stay under 55% of the time.
Pirates vs Reds: Betting Tips
- Head to Head: Pittsburgh at $2.25 with TAB
- Line: Pirates +1.5 at $1.72 with TAB
- Total Runs: Under 8 at $1.91 with TAB
Stats Insider's Pirates vs Reds best bets are based on world-class modelling and gambling expertise to give you the best possible advice every day of the year.
While the Reds have a higher chance of winning the game, betting on the Pirates to win is our preferred option because of the 2.6% edge found when comparing our data-led probabilities to the odds currently available.
Making use of the edges published on Stats Insider is pivotal to being profitable in the long run.
Pirates vs Reds: Prediction
Stats Insider provides full betting coverage of the Pittsburgh vs Cincinnati game on Wednesday, including data-driven predictions and expert tips.
Our model updates regularly, so bookmark this page for the latest betting tips before the Pittsburgh vs Cincinnati game.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, plus predictions for a wide range of other sports.
Pirates vs Reds: Essential Details
The match-up between the Pirates and Reds at PNC Park is scheduled to begin at 8:40am AEST on Wednesday.
- Teams: Pittsburgh Pirates vs Cincinnati Reds
- Date: Wednesday 21 May 2025
- Time: 8:40am AEST
- Venue: PNC Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Pittsburgh vs Cincinnati predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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