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Pirates vs Nationals Prediction and MLB Tips - 16 April 2025

The Pittsburgh Pirates will take on the Washington Nationals in MLB action at PNC Park on Wednesday, beginning at 8:40am AEST.

The Pirates will have Mitch Keller (1-1, 4.24 ERA) start, pitting him against Jake Irvin (0-0, 5.62 ERA) for the Nationals.

This article features Stats Insider's prediction and tips for the Pirates vs Nationals game, along with the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the result of Wednesday's Pittsburgh vs Washington MLB match-up 10,000 times.

Our proven predictive analytics model currently gives the Pirates a 55% chance of beating the Nationals at PNC Park.

Pirates vs Nationals: Odds

The current betting odds in Australia for Wednesday's MLB game at PNC Park are listed here:

  • Head to Head: Pirates $1.74, Nationals $2.15
  • Line: Pirates -1.5 ($2.50), Nationals +1.5 ($1.56)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.74 and the Nationals at $2.15.

The Pirates are 1.5-run favourites against the Nationals, with odds of $2.50 available at TAB.

For the underdog Nationals (+1.5) to cover the line, TAB offers odds of $1.56.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Nationals (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to stay under 56% of the time.

Pirates vs Nationals: Best Bets

  • Head to Head: Washington at $2.15 with TAB
  • Line: Nationals +1.5 at $1.56 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

These Pirates vs Nationals betting tips are based on detailed modelling and gambling expertise to bring you the best possible advice every day of the year.

While the Pirates have a higher chance of winning the game, betting on the Nationals to win is our preferred option because of the edge found when comparing our data-led probabilities to the odds currently on offer.

Taking advantage of the edges published on Stats Insider is pivotal to achieving long-term profitability.

Pirates vs Nationals: Prediction

Stats Insider provides full coverage of the Pittsburgh vs Washington game on Wednesday, including data-driven predictions and expert tips.

Remember, our model updates regularly, so bookmark this article for the latest betting predictions before the Pittsburgh vs Washington match-up.

As always, see our Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.

Pirates vs Nationals: Essential Details

The game between the Pirates and Nationals at PNC Park is scheduled to start at 8:40am AEST on Wednesday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Pittsburgh vs Washington predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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