Pirates vs Cardinals Prediction and MLB Tips - 24 September 2026
Last updated: Sep 23, 2026, 10:41PM | Published: Sep 23, 2026, 3:27AM
The Pittsburgh Pirates will take on the St. Louis Cardinals in MLB action at PNC Park on Thursday, beginning at 8:40am AEST.
Lake Bachar (1-4, 3.56 ERA) will start for the Pirates, while the Cardinals will counter with Matthew Liberatore (5-14, 5.36 ERA).
This article features Stats Insider's top betting tips for the Pirates vs Cardinals game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted machine learning and data, Stats Insider has simulated the outcome of Thursday's Pittsburgh vs St. Louis MLB game 10,000 times.
Our leading predictive analytics model gives the Pirates a 57% chance of defeating the Cardinals at PNC Park.
Pirates vs Cardinals: Odds
The latest betting odds in Australia for Thursday's MLB game at PNC Park are shown below:
- Head to Head: Pirates $1.74, Cardinals $2.14
- Line: Pirates -1.5 ($2.54), Cardinals +1.5 ($1.51)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.74 and the Cardinals at $2.14.
The Pirates are listed as 1.5-run favourites against the Cardinals, with odds of $2.54 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.51.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 61% of the time, while the 7-run over/under is expected to go over 55% of the time.
Pirates vs Cardinals: Best Bets
- Head to Head: Pittsburgh at $1.74 with TAB
- Line: Pirates -1.5 at $2.54 with TAB
- Total Runs: Over 7 at $1.91 with TAB
Our Pirates vs Cardinals predictions are based on market-leading modelling and gambling expertise to bring you the best possible advice around the clock.
Although the Cardinals are more likely to cover the line, our best bet of Pirates -1.5 is based on the likelihood of that happening, as projected by our predictive analytics model, and the top odds available.
Pirates vs Cardinals: Prediction
Stats Insider provides full coverage of the Pittsburgh vs St. Louis game on Thursday, including data-driven predictions and computer tips.
Our model updates frequently, so bookmark this page for the latest betting tips before the Pittsburgh vs St. Louis game.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, plus predictions for a wide range of other sports.
Pirates vs Cardinals: Essential Details
The game between the Pirates and Cardinals at PNC Park is scheduled to commence at 8:40am AEST on Thursday.
- Teams: Pittsburgh Pirates vs St. Louis Cardinals
- Date: Thursday 24 September 2026
- Time: 8:40am AEST
- Venue: PNC Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Pittsburgh vs St. Louis predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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