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Pirates vs Cardinals Prediction and MLB Tips - 2 July 2025

The Pittsburgh Pirates will sqaure off with the St. Louis Cardinals in MLB action at PNC Park on Wednesday, beginning at 8:40am AEST.

Paul Skenes (4-7, 2.12 ERA) will be on the bump for the Pirates, up against Andre Pallante (5-4, 4.43 ERA) for the Cardinals.

This article features Stats Insider's free betting tips for the Pirates vs Cardinals game, plus the latest betting odds in Australia.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the result of Wednesday's Pittsburgh vs St. Louis MLB game 10,000 times.

Our independent predictive analytics model currently gives the Pirates a 60% chance of winning against the Cardinals at PNC Park.

Pirates vs Cardinals: Odds

The latest betting odds in Australia for Wednesday's MLB game at PNC Park are listed below:

  • Head to Head: Pirates $1.60, Cardinals $2.39
  • Line: Pirates -1.5 ($2.34), Cardinals +1.5 ($1.62)
  • Total (Over/Under 7.167 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.60 and the Cardinals at $2.39.

The Pirates are 1.5-run favourites against the Cardinals, with odds of $2.34 available at TAB.

For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.62.

The over/under for total runs scored is set at 7.167 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 60% of the time, while the 7.167-run over/under is expected to go over 51% of the time.

Pirates vs Cardinals: Betting Tips

  • Head to Head: St. Louis at $2.39 with TAB
  • Line: Cardinals +1.5 at $1.62 with TAB
  • Total Runs: Over 7.167 at $1.91 with TAB

Our Pirates vs Cardinals predictions are based on market-leading modelling and betting expertise to help you place better bets with your chosen online bookie.

While the Pirates have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the edge identified when comparing our data-driven probabilities to the odds currently available.

Making use of the edges published on Stats Insider is one of the keys to being a profitable bettor in the long run.

Pirates vs Cardinals: Prediction

Stats Insider provides full betting coverage of the Pittsburgh vs St. Louis game on Wednesday, including data-driven predictions and top betting tips.

Our model updates regularly, so refresh this article for the latest betting analysis before the Pittsburgh vs St. Louis match-up.

As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.

Pirates vs Cardinals: Essential Details

The match-up between the Pirates and Cardinals at PNC Park is scheduled to begin at 8:40am AEST on Wednesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Pittsburgh vs St. Louis predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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