Pirates vs Cardinals Prediction and MLB Tips - 1 May 2026
Last updated: Apr 30, 2026, 4:33PM | Published: Apr 29, 2026, 5:33PM
The Pittsburgh Pirates will sqaure off with the St. Louis Cardinals in MLB action at PNC Park on Friday, beginning at 2:35am AEST.
The Pirates will send Paul Skenes (4-1, 2.48 ERA) to the mound, while the Cardinals will counter with Hunter Dobbins (0-0, 0.00 ERA).
This article features Stats Insider's prediction and tips for the Pirates vs Cardinals game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Friday's Pittsburgh vs St. Louis MLB match-up 10,000 times.
Our leading predictive analytics model currently gives the Pirates a 67% chance of winning against the Cardinals at PNC Park.
Pirates vs Cardinals: Odds
The latest betting odds in Australia for Friday's MLB game at PNC Park are shown below:
- Head to Head: Pirates $1.40, Cardinals $3.05
- Line: Pirates -1.5 ($1.91), Cardinals +1.5 ($1.91)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.40 and the Cardinals at $3.05.
The Pirates are listed as 1.5-run favourites against the Cardinals, with odds of $1.91 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.91.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 51% of the time, while the 7-run over/under is expected to go over 51% of the time.
Pirates vs Cardinals: Betting Tips
- Head to Head: St. Louis at $3.05 with TAB
- Line: Cardinals +1.5 at $1.91 with TAB
- Total Runs: Over 7 at $1.91 with TAB
These Pirates vs Cardinals predictions are based on detailed simulations and betting expertise to help you place more informed bets with your chosen online bookie.
While the Pirates have a higher chance of winning the game, betting on the Cardinals to win is our preferred option due to the 1.1% edge identified when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges seen on Stats Insider is crucial to achieving long-term profitability.
Pirates vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Pittsburgh vs St. Louis game on Friday, including data-driven predictions and top betting tips.
Our model updates frequently, so bookmark this article for the latest betting analysis before the Pittsburgh vs St. Louis match-up.
As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.
Pirates vs Cardinals: Essential Details
The game between the Pirates and Cardinals at PNC Park is scheduled to start at 2:35am AEST on Friday.
- Teams: Pittsburgh Pirates vs St. Louis Cardinals
- Date: Friday 1 May 2026
- Time: 2:35am AEST
- Venue: PNC Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Pittsburgh vs St. Louis predictions are based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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