Pirates vs Astros Prediction and MLB Tips - 4 June 2025
Last updated: Jun 3, 2025, 10:40PM | Published: Jun 2, 2025, 6:29PM
The Pittsburgh Pirates will take on the Houston Astros in MLB action at PNC Park on Wednesday, beginning at 8:40am AEST.
Paul Skenes (4-5, 2.15 ERA) will be on the bump for the Pirates, pitting him against Lance McCullers (0-1, 5.89 ERA) for the Astros.
This article features Stats Insider's prediction and tips for the Pirates vs Astros game, as well as the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Wednesday's Pittsburgh vs Houston MLB match-up 10,000 times.
Our proven predictive analytics model gives the Pirates a 59% chance of beating the Astros at PNC Park.
Pirates vs Astros: Odds
The current betting odds in Australia for Wednesday's MLB game at PNC Park are listed below:
- Head to Head: Pirates $1.61, Astros $2.40
- Line: Pirates -1.5 ($2.35), Astros +1.5 ($1.62)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Pirates at $1.61 and the Astros at $2.40.
The Pirates are listed as 1.5-run favourites against the Astros, with odds of $2.35 available at TAB.
For the underdog Astros (+1.5) to cover the line, TAB offers odds of $1.62.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Astros (+1.5) are predicted to cover the line 62% of the time, while the 7-run over/under is expected to stay under 53% of the time.
Pirates vs Astros: Best Bets
- Head to Head: Houston at $2.40 with TAB
- Line: Astros +1.5 at $1.62 with TAB
- Total Runs: Under 7 at $1.91 with TAB
Today's Pirates vs Astros best bets are based on market-leading simulations and betting experience to help you place smarter bets with your chosen online bookie.
While the Pirates have a higher chance of winning the game, betting on the Astros to win is our recommended option because of the 1.4% edge identified when comparing our data-led probabilities to the odds currently on offer.
Making use of the edges seen on Stats Insider is crucial to being a profitable sports bettor in the long run.
Pirates vs Astros: Prediction
Stats Insider provides full coverage of the Pittsburgh vs Houston game on Wednesday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so refresh this page for the latest betting tips before the Pittsburgh vs Houston game.
As always, see our Best Bets for the best tips for every MLB game, plus predictions for a wide range of other sports.
Pirates vs Astros: Essential Details
The game between the Pirates and Astros at PNC Park is scheduled to start at 8:40am AEST on Wednesday.
- Teams: Pittsburgh Pirates vs Houston Astros
- Date: Wednesday 4 June 2025
- Time: 8:40am AEST
- Venue: PNC Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Pittsburgh vs Houston predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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