Panthers vs Tigers Prediction and Tips - NRL Round 21, 2025

The Panthers will take on the Tigers in NRL Round 21 action at Panthers Stadium on Saturday, beginning at 5:30pm AEST.

This article features Stats Insider's free betting tips for the Panthers vs Tigers game, plus the latest betting odds.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the outcome of Saturday's Penrith vs Wests NRL match 10,000 times.

Our leading predictive analytics model currently gives the Panthers an 81% chance of winning against the Tigers at Panthers Stadium.

Panthers vs Tigers: Odds

The latest Bet365 betting odds for Saturday's NRL clash at Panthers Stadium are shown here:

• Head to Head: Panthers $1.25, Tigers $4.00
• Line: Panthers -12.5 ($1.91), Tigers +12.5 ($1.91)
• Total (Over/Under 46.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $1.25 and the Tigers at $4.00.

The Panthers are listed as 12.5-point favourites against the Tigers, with odds of $1.91 available at Bet365.

For the underdog Tigers (+12.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 46.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Panthers (-12.5) are predicted to cover the line 53% of the time, while the 46.5-point over/under is expected to stay under 54% of the time.

Panthers vs Tigers: Betting Tips

• Head to Head: Panthers at $1.25 with Bet365
• Line: Panthers -12.5 at $1.91 with Bet365
• Total Points: Under 46.5 at $1.91 with Bet365

Stats Insider's Panthers vs Tigers betting tips are based on complex modelling and gambling intelligence to provide you with the best possible advice every time.

Panthers vs Tigers: Prediction

Stats Insider's predicted final score for Panthers vs Tigers at Panthers Stadium on Saturday is the Panthers winning 29-16.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the Panthers vs Tigers match on Saturday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so refresh this article for the latest betting tips before the Panthers vs Tigers game.

As always, see our Best Bets for betting tips on every NRL match, as well as predictions for a wide range of other sports.

Panthers vs Tigers: Essential Details

The NRL Round 21 clash between the Panthers and Tigers at Panthers Stadium is scheduled to begin at 5:30pm AEST on Saturday.

• Teams: Penrith Panthers vs Wests Tigers
• Date: Saturday 26 July 2025
• Kick-off: 5:30pm AEST
• Location: Panthers Stadium

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Panthers vs Tigers predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our rugby league tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.

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