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Panthers vs Tigers Prediction and Tips - NRL Round 21, 2025

The Panthers will face the Tigers in NRL Round 21 action at Panthers Stadium on Saturday, with kick-off at 5:30pm AEST.

This article features Stats Insider's free betting tips for the Panthers vs Tigers game, along with the latest betting odds and try scorer tips.

Who Will Win?

Using advanced machine learning and data, Stats Insider has simulated the outcome of Saturday's Penrith vs Wests NRL match 10,000 times.

Our independent predictive analytics model gives the Panthers an 82% chance of beating the Tigers at Panthers Stadium.

Panthers vs Tigers: Odds

The latest Bet365 betting odds for Saturday's NRL clash at Panthers Stadium are listed below:

  • Head to Head: Panthers $1.22, Tigers $4.50
  • Line: Panthers -14.5 ($1.91), Tigers +14.5 ($1.91)
  • Total (Over/Under 46.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $1.22 and the Tigers at $4.50.

The Panthers are listed as 14.5-point favourites against the Tigers, with odds of $1.91 available at Bet365.

For the underdog Tigers (+14.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 46.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Tigers (+14.5) are predicted to cover the line 52% of the time, while the 46.5-point over/under is expected to stay under 54% of the time.

Panthers vs Tigers: Betting Tips

  • Head to Head: Panthers at $1.22 with Bet365
  • Line: Tigers +14.5 at $1.91 with Bet365
  • Total Points: Under 46.5 at $1.91 with Bet365

These Panthers vs Tigers best bets are based on complex modelling and wagering experience to help you place smarter bets with your chosen online bookie.

Panthers vs Tigers: Prediction

Stats Insider's predicted final score for Panthers vs Tigers at Panthers Stadium this Saturday is the Panthers winning 29-15.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full coverage of the Panthers vs Tigers match on Saturday, including data-driven predictions and the best betting tips.

18+. Odds correct at time of publishing and subject to change.

Panthers vs Tigers: Try Scorers

Searching for Panthers vs Tigers try scorers? The data is in.

According to Stats Insider, the Panthers' Brian To'o is the most likely player to score the first try in Penrith vs Wests.

To'o has a 9.6% chance of scoring the first try at Panthers Stadium, while the Panthers star has a 53.0% chance of scoring a try at any time during the match.

Scroll down for our full list of first try scorer and anytime try scorer probabilities.

First Try Scorer Tips

Penrith Panthers

  • Brian To'o: 9.6% probability
  • Thomas Jenkins: 8.8% probability
  • Casey McLean: 6.1% probability
  • Izack Tago: 6.1% probability
  • Luke Garner: 6.1% probability

Wests Tigers

  • Izaac Tu'itupou: 5.0% probability
  • Jeral Skelton: 5.0% probability
  • Starford To'a: 4.6% probability
  • Taylan May: 3.1% probability
  • Sunia Turuva: 3.0% probability

Anytime Try Scorer Tips

Penrith Panthers

  • Brian To'o: 53.0% probability
  • Thomas Jenkins: 50.6% probability
  • Casey McLean: 39.7% probability
  • Dylan Edwards: 38.0% probability
  • Izack Tago: 38.0% probability

Wests Tigers

  • Jeral Skelton: 35.8% probability
  • Izaac Tu'itupou: 32.5% probability
  • Starford To'a: 30.6% probability
  • Taylan May: 22.8% probability
  • Sunia Turuva: 22.6% probability

Remember, our model updates frequently, so refresh this page for the latest betting tips before the Panthers vs Tigers match.

As always, see Stats Insider's Best Bets to get betting tips on every NRL match, as well as predictions for a wide range of other sports.

Panthers vs Tigers: Essential Details

The NRL Round 21 clash between the Panthers and Tigers at Panthers Stadium is scheduled to start at 5:30pm AEST on Saturday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Panthers vs Tigers predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our rugby league tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our NRL predictions for betting purposes, it's important that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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More on the NRL

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