Panthers vs Knights Prediction and Tips - NRL Round 12, 2025
Last updated: May 24, 2025, 7:30AM | Published: May 18, 2025, 3:55AM
The Panthers will face the Knights in NRL Round 12 action at Panthers Stadium on Saturday, with kick-off at 5:30pm AEST.
This article features Stats Insider's top betting tips for the Panthers vs Knights game, as well as the latest betting odds and try scorer tips.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the outcome of Saturday's Penrith vs Newcastle NRL match 10,000 times.
Our independent predictive analytics model gives the Panthers a 72% chance of defeating the Knights in Round 12 of the 2025 NRL season.
Panthers vs Knights: Odds
The current Bet365 betting odds for Saturday's NRL clash at Panthers Stadium are shown below:
- Head to Head: Panthers $1.54, Knights $2.55
- Line: Panthers -5.5 ($1.91), Knights +5.5 ($1.91)
- Total (Over/Under 42.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $1.54 and the Knights at $2.55.
The Panthers are listed as 5.5-point favourites against the Knights, with odds of $1.91 available at Bet365.
For the underdog Knights (+5.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 42.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Panthers (-5.5) are predicted to cover the line 59% of the time, while the 42.5-point over/under is expected to go over 53% of the time.
Panthers vs Knights: Best Bets
- Head to Head: Panthers at $1.54 with Bet365
- Line: Panthers -5.5 at $1.91 with Bet365
- Total Points: Over 42.5 at $1.91 with Bet365
If you see a 🔥, that means it's one of Stats Insider's best bets for today across any sport.
These Panthers vs Knights betting tips are based on complex modelling and wagering experience to help you place more informed bets with your chosen online bookie.
Panthers vs Knights: Prediction
Stats Insider's predicted final score for Panthers vs Knights at Panthers Stadium on Saturday is the Panthers winning 26-17.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Panthers vs Knights match on Saturday, including data-driven predictions and free betting tips.
18+. Odds correct at time of publishing and subject to change.Panthers vs Knights: Try Scorers
Are you looking for Panthers vs Knights try scorers? The latest data is in.
According to Stats Insider, the Panthers' Jesse McLean is the most likely player to score the first try in Penrith vs Newcastle.
McLean has a 8.9% chance of scoring the first try at Panthers Stadium, while the Panthers star has a 45.4% chance of scoring a try at any time during the match.
Scroll down for the full list of first try scorer and anytime try scorer probabilities.
First Try Scorer Tips
Penrith Panthers
- Jesse McLean: 8.9% probability
- Paul Alamoti: 7.7% probability
- Casey McLean: 6.2% probability
- Thomas Jenkins: 5.6% probability
- Blaize Talagi: 4.1% probability
Newcastle Knights
- James Schiller: 7.3% probability
- Fletcher Hunt: 5.8% probability
- Fletcher Sharpe: 4.3% probability
- Kyle McCarthy: 3.9% probability
- Dylan Lucas: 3.6% probability
Anytime Try Scorer Tips
Penrith Panthers
- Jesse McLean: 45.4% probability
- Paul Alamoti: 42.7% probability
- Casey McLean: 36.6% probability
- Thomas Jenkins: 32.4% probability
- Daine Laurie: 25.2% probability
Newcastle Knights
- James Schiller: 41.9% probability
- Fletcher Hunt: 35.4% probability
- Fletcher Sharpe: 28.4% probability
- Kyle McCarthy: 26.1% probability
- Dane Gagai: 22.1% probability
Our model updates frequently, so refresh this page for the latest betting predictions before the Panthers vs Knights match.
As always, see our Best Bets to get betting tips on every NRL match, as well as predictions for a wide range of other sports.
Panthers vs Knights: Essential Details
The NRL Round 12 clash between the Panthers and Knights at Panthers Stadium is scheduled to begin at 5:30pm AEST on Saturday.
- Teams: Penrith Panthers vs Newcastle Knights
- Date: Saturday 24 May 2025
- Kick-off: 5:30pm AEST
- Location: Panthers Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Panthers vs Knights predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our rugby league tips are accurate and reliable, giving you the confidence to make informed decisions.
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