Panthers vs Buccaneers Prediction and Preview - NFL Week 16, 2025
Last updated: Dec 21, 2025, 6:01PM | Published: Dec 14, 2025, 5:01AM
The Carolina Panthers will face the Tampa Bay Buccaneers in NFL Week 16 action at Bank of America Stadium on Monday, commencing at 5:00am AEDT.
This article features Stats Insider's top betting tips for the Panthers vs Buccaneers game, along with the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Monday's Carolina vs Tampa Bay NFL match-up 10,000 times.
Our independent predictive analytics model gives the Buccaneers a 61% chance of winning against the Panthers at Bank of America Stadium.
Panthers vs Buccaneers: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Bank of America Stadium are shown below:
- Head to Head: Panthers $2.35, Buccaneers $1.62
- Line: Panthers +3 ($1.91), Buccaneers -3 ($1.91)
- Total (Over/Under 45 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Panthers at $2.35 and the Buccaneers at $1.62.
The Panthers are 3-point underdogs against the Buccaneers, with odds of $1.91 available at Bet365.
For the favourite Buccaneers (-3) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 45 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the bookmakers have got it right and both the Panthers and the Buccaneers have a 50% chance of covering the line.
The 45-point over/under is expected to stay under 51% of the time.
Panthers vs Buccaneers: Best Bets
- Head to Head: Tampa Bay at $1.62 with Bet365
- Line: Buccaneers -3 at $1.91 with Bet365
- Total Points: Under 45 at $1.91 with Bet365
Stats Insider's Panthers vs Buccaneers betting tips are based on complex modelling and betting intelligence to help you place smarter bets with your chosen online bookie.
Panthers vs Buccaneers: Prediction
Stats Insider's predicted final score for Panthers vs Buccaneers at Bank of America Stadium in Week 16 is the Buccaneers winning 23-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Carolina vs Tampa Bay game in Week 16, including data-driven predictions and free betting tips.
For in-depth analysis from US experts,, check out Dimers' detailed Panthers vs Buccaneers prediction.
18+. Odds correct at time of publishing and subject to change.Panthers vs Buccaneers: TD Scorer Tips
Who will score the first touchdown in Panthers vs Buccaneers? The latest data is in.
According to Stats Insider, Tampa Bay's Mike Evans is the most likely player to score the first touchdown in Panthers vs Buccaneers.
Evans has a 10.0% chance of getting in for six first at Bank of America Stadium, while the Buccaneers WR has a 44.8% chance of scoring an anytime touchdown.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Panthers First TD Tips
- Rico Dowdle: 9.5% probability
- Tetairoa McMillan: 8.4% probability
- Jalen Coker: 5.5% probability
- Chuba Hubbard: 4.2% probability
- Xavier Legette: 3.9% probability
Buccaneers First TD Tips
- Mike Evans: 10.0% probability
- Bucky Irving: 8.9% probability
- Chris Godwin: 6.5% probability
- Emeka Egbuka: 5.6% probability
- Sean Tucker: 5.1% probability
Anytime Touchdown Scorer Tips
Panthers Anytime TD Tips
- Rico Dowdle: 41.7% probability
- Tetairoa McMillan: 38.0% probability
- Jalen Coker: 26.6% probability
- Chuba Hubbard: 21.2% probability
- Xavier Legette: 20.1% probability
Buccaneers Anytime TD Tips
- Mike Evans: 44.8% probability
- Bucky Irving: 41.1% probability
- Chris Godwin: 32.1% probability
- Emeka Egbuka: 28.4% probability
- Sean Tucker: 26.0% probability
Panthers-Buccaneers Projected Player Stats
Of the starting quarterbacks, the Panthers' Bryce Young is projected for 214 passing yards. The Buccaneers' Baker Mayfield is expected to throw for 233 yards.
Panthers Starting QB
- Bryce Young: 214 projected passing yards
Buccaneers Starting QB
- Baker Mayfield: 233 projected passing yards
Panthers Rushing Yards
- Rico Dowdle: 59 projected yards
- Chuba Hubbard: 33 projected yards
- Bryce Young: 16 projected yards
Buccaneers Rushing Yards
- Bucky Irving: 67 projected yards
- Baker Mayfield: 18 projected yards
- Sean Tucker: 17 projected yards
Panthers Receiving Yards
- Tetairoa McMillan: 62 projected yards
- Jalen Coker: 45 projected yards
- Xavier Legette: 28 projected yards
- Ja'Tavion Sanders: 19 projected yards
- Rico Dowdle: 17 projected yards
Buccaneers Receiving Yards
- Mike Evans: 68 projected yards
- Emeka Egbuka: 41 projected yards
- Chris Godwin: 39 projected yards
- Cade Otton: 26 projected yards
- Jalen McMillan: 26 projected yards
Our model updates frequently, so keep checking this article for the latest betting analysis before the Carolina vs Tampa Bay game.
As always, see our Best Bets to get betting tips for every NFL game, plus predictions for a wide range of other sports.
Panthers vs Buccaneers: Week 16 Essential Details
The NFL Week 16 game between the Panthers and Buccaneers at Bank of America Stadium is scheduled to commence at 5:00am AEDT on Monday.
- Teams: Carolina Panthers vs Tampa Bay Buccaneers
- Date: Monday 22 December 2025
- Time: 5:00am AEDT
- Venue: Bank of America Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Carolina vs Tampa Bay predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our NFL predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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