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Padres vs Royals Prediction and MLB Tips - 22 June 2025

The San Diego Padres will take on the Kansas City Royals in MLB action at PETCO Park on Sunday, commencing at 9:15am AEST.

The Padres will have Dylan Cease (2-6, 4.69 ERA) start, pitting him against Noah Cameron (2-2, 1.91 ERA) for the Royals.

This article features Stats Insider's free betting tips for the Padres vs Royals game, as well as the latest betting odds in Australia.

Who Will Win?

Based on advanced computer power and data, Stats Insider has simulated the result of Sunday's San Diego vs Kansas City MLB match-up 10,000 times.

Our leading predictive analytics model currently gives the Padres a 58% chance of beating the Royals at PETCO Park.

Padres vs Royals: Odds

The latest betting odds in Australia for Sunday's MLB game at PETCO Park are shown here:

  • Head to Head: Padres $1.65, Royals $2.30
  • Line: Padres -1.5 ($2.45), Royals +1.5 ($1.59)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.65 and the Royals at $2.30.

The Padres are 1.5-run favourites against the Royals, with odds of $2.45 available at TAB.

For the underdog Royals (+1.5) to cover the line, TAB offers odds of $1.59.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Royals (+1.5) are predicted to cover the line 62% of the time, while the 7.5-run over/under is expected to stay under 55% of the time.

Padres vs Royals: Betting Tips

  • Head to Head: Kansas City at $2.30 with TAB
  • Line: Royals +1.5 at $1.59 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

These Padres vs Royals predictions are based on detailed simulations and wagering experience to help you place more informed bets with your chosen online bookie.

While the Padres have a higher chance of winning the game, betting on the Royals to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently available.

Making use of the edges published here at Stats Insider is pivotal to achieving long-term profitability.

Padres vs Royals: Prediction

Stats Insider provides full betting coverage of the San Diego vs Kansas City game on Sunday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so refresh this article for the latest betting tips before the San Diego vs Kansas City game.

As always, see our Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.

Padres vs Royals: Essential Details

The game between the Padres and Royals at PETCO Park is scheduled to start at 9:15am AEST on Sunday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our San Diego vs Kansas City predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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