Padres vs Reds Prediction and MLB Tips - 10 September 2025
Last updated: Sep 9, 2025, 5:56AM | Published: Sep 8, 2025, 11:30PM
The San Diego Padres will sqaure off with the Cincinnati Reds in MLB action at PETCO Park on Wednesday, starting at 11:40am AEST.
The Padres will send Michael King (4-2, 2.81 ERA) to the mound, while the Reds are going with Zack Littell (9-8, 3.81 ERA).
This article features Stats Insider's best betting tips for the Padres vs Reds game, as well as the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the outcome of Wednesday's San Diego vs Cincinnati MLB match-up 10,000 times.
Our independent predictive analytics model gives the Padres a 64% chance of winning against the Reds at PETCO Park.
Padres vs Reds: Odds
The latest betting odds in Australia for Wednesday's MLB game at PETCO Park are shown below:
- Head to Head: Padres $1.54, Reds $2.52
- Line: Padres -1.5 ($2.16), Reds +1.5 ($1.71)
- Total (Over/Under 7.6 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.54 and the Reds at $2.52.
The Padres are 1.5-run favourites against the Reds, with odds of $2.16 available at TAB.
For the underdog Reds (+1.5) to cover the line, TAB offers odds of $1.71.
The over/under for total runs scored is set at 7.6 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Reds (+1.5) are predicted to cover the line 55% of the time, while the 7.6-run over/under is expected to go over 51% of the time.
Padres vs Reds: Betting Tips
- Head to Head: San Diego at $1.54 with TAB
- Line: Padres -1.5 at $2.16 with TAB
- Total Runs: Over 7.6 at $1.91 with TAB
These Padres vs Reds best bets are based on world-class modelling and betting experience to give you the best possible advice every day of the year.
Although the Reds are more likely to cover the line, our best bet of Padres -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the top odds available.
Padres vs Reds: Prediction
Stats Insider provides full coverage of the San Diego vs Cincinnati game on Wednesday, including data-driven predictions and expert tips.
Remember, our model updates frequently, so bookmark this page for the latest betting analysis before the San Diego vs Cincinnati game.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.
Padres vs Reds: Essential Details
The game between the Padres and Reds at PETCO Park is scheduled to start at 11:40am AEST on Wednesday.
- Teams: San Diego Padres vs Cincinnati Reds
- Date: Wednesday 10 September 2025
- Time: 11:40am AEST
- Venue: PETCO Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our San Diego vs Cincinnati predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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