Padres vs Orioles Prediction and MLB Tips - 4 September 2025
Last updated: Sep 3, 2025, 8:09PM | Published: Sep 2, 2025, 7:32PM
The San Diego Padres will sqaure off with the Baltimore Orioles in MLB action at PETCO Park on Thursday, starting at 6:10am AEST.
The Padres will send Nestor Cortes (2-3, 5.06 ERA) to the mound, while the Orioles will counter with Cade Povich (2-7, 5.04 ERA).
This article features Stats Insider's prediction and tips for the Padres vs Orioles game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the result of Thursday's San Diego vs Baltimore MLB game 10,000 times.
Our proven predictive analytics model currently gives the Padres a 61% chance of beating the Orioles at PETCO Park.
Padres vs Orioles: Odds
The latest betting odds in Australia for Thursday's MLB game at PETCO Park are shown below:
- Head to Head: Padres $1.53, Orioles $2.55
- Line: Padres -1.5 ($2.16), Orioles +1.5 ($1.72)
- Total (Over/Under 8.222 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.53 and the Orioles at $2.55.
The Padres are 1.5-run favourites against the Orioles, with odds of $2.16 available at TAB.
For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.72.
The over/under for total runs scored is set at 8.222 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 57% of the time, while the 8.222-run over/under is expected to stay under 52% of the time.
Padres vs Orioles: Betting Tips
- Head to Head: Baltimore at $2.55 with TAB
- Line: Orioles +1.5 at $1.72 with TAB
- Total Runs: Under 8.222 at $1.91 with TAB
These Padres vs Orioles betting tips are based on market-leading modelling and wagering intelligence to give you the best possible advice around the clock.
While the Padres have a higher chance of winning the game, betting on the Orioles to win is our recommended option due to the 1.1% edge found when comparing our data-driven probabilities to the odds currently available.
Making use of the edges seen on Stats Insider is pivotal to achieving long-term success as a bettor.
Padres vs Orioles: Prediction
Stats Insider provides full betting coverage of the San Diego vs Baltimore game on Thursday, including data-driven predictions and expert tips.
Remember, our model updates frequently, so refresh this article for the latest betting tips before the San Diego vs Baltimore match-up.
As always, see our Best Bets for the best tips on every MLB game, as well as predictions for a wide range of other sports.
Padres vs Orioles: Essential Details
The match-up between the Padres and Orioles at PETCO Park is scheduled to commence at 6:10am AEST on Thursday.
- Teams: San Diego Padres vs Baltimore Orioles
- Date: Thursday 4 September 2025
- Time: 6:10am AEST
- Venue: PETCO Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our San Diego vs Baltimore predictions are based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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