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Padres vs Orioles Prediction and MLB Tips - 3 September 2025

The San Diego Padres will take on the Baltimore Orioles in MLB action at PETCO Park on Wednesday, starting at 11:40am AEST.

Yu Darvish (3-4, 5.66 ERA) will be on the bump for the Padres, up against Tyler Wells (0-0, 0.00 ERA) for the Orioles.

This article features Stats Insider's free betting tips for the Padres vs Orioles game, plus the latest betting odds in Australia.

Who Will Win?

Based on trusted machine learning and data, Stats Insider has simulated the result of Wednesday's San Diego vs Baltimore MLB match-up 10,000 times.

Our proven predictive analytics model currently gives the Padres a 63% chance of defeating the Orioles at PETCO Park.

Padres vs Orioles: Odds

The current betting odds in Australia for Wednesday's MLB game at PETCO Park are shown below:

  • Head to Head: Padres $1.56, Orioles $2.50
  • Line: Padres -1.5 ($2.20), Orioles +1.5 ($1.72)
  • Total (Over/Under 8 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.56 and the Orioles at $2.50.

The Padres are listed as 1.5-run favourites against the Orioles, with odds of $2.20 available at TAB.

For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.72.

The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 57% of the time, while the 8-run over/under is expected to is considered an equal 50-50 chance of hitting.

Padres vs Orioles: Best Bets

  • Head to Head: San Diego at $1.56 with TAB
  • Line: Orioles +1.5 at $1.72 with TAB
  • Total Runs: Under 8 at $1.91 with TAB

Our Padres vs Orioles best bets are based on market-leading simulations and gambling experience to provide you with the best possible advice every day of the year.

Padres vs Orioles: Prediction

Stats Insider provides full coverage of the San Diego vs Baltimore game on Wednesday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so refresh this article for the latest betting predictions before the San Diego vs Baltimore game.

As always, see Stats Insider's Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.

Padres vs Orioles: Essential Details

The game between the Padres and Orioles at PETCO Park is scheduled to begin at 11:40am AEST on Wednesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our San Diego vs Baltimore predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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