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Padres vs Orioles Prediction and MLB Tips - 2 September 2025

The San Diego Padres will face the Baltimore Orioles in MLB action at PETCO Park on Tuesday, beginning at 8:40am AEST.

The Padres will send Dylan Cease (6-11, 4.82 ERA) to the mound, while the Orioles are going with Kyle Bradish (0-1, 3.00 ERA).

This article features Stats Insider's free betting tips for the Padres vs Orioles game, plus the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Tuesday's San Diego vs Baltimore MLB match-up 10,000 times.

Our independent predictive analytics model gives the Padres a 63% chance of winning against the Orioles at PETCO Park.

Padres vs Orioles: Odds

The latest betting odds in Australia for Tuesday's MLB game at PETCO Park are listed here:

  • Head to Head: Padres $1.59, Orioles $2.45
  • Line: Padres -1.5 ($2.35), Orioles +1.5 ($1.62)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.59 and the Orioles at $2.45.

The Padres are 1.5-run favourites against the Orioles, with odds of $2.35 available at TAB.

For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.62.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 58% of the time, while the 7.5-run over/under is expected to stay under 53% of the time.

Padres vs Orioles: Betting Tips

  • Head to Head: San Diego at $1.59 with TAB
  • Line: Padres -1.5 at $2.35 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

These Padres vs Orioles betting tips are based on complex modelling and wagering experience to help you place better bets with your chosen online bookie.

Although the Orioles are more likely to cover the line, our best bet of Padres -1.5 is based on the probability of that happening, as suggested by our predictive analytics model, and the top odds available.

Padres vs Orioles: Prediction

Stats Insider provides full coverage of the San Diego vs Baltimore game on Tuesday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates frequently, so keep checking this article for the latest betting analysis before the San Diego vs Baltimore game.

As always, see our Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.

Padres vs Orioles: Essential Details

The match-up between the Padres and Orioles at PETCO Park is scheduled to commence at 8:40am AEST on Tuesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our San Diego vs Baltimore predictions are based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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