Padres vs Giants Prediction and MLB Tips - 20 August 2025
Last updated: Aug 20, 2025, 1:41AM | Published: Aug 18, 2025, 8:58PM
The San Diego Padres will face the San Francisco Giants in MLB action at PETCO Park on Wednesday, beginning at 11:40am AEST.
Nick Pivetta (12-4, 2.87 ERA) will be on the bump for the Padres, pitting him against Kai-Wei Teng (1-2, 9.90 ERA) for the Giants.
This article features Stats Insider's best betting tips for the Padres vs Giants game, as well as the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Wednesday's San Diego vs San Francisco MLB game 10,000 times.
Our leading predictive analytics model gives the Padres a 65% chance of defeating the Giants at PETCO Park.
Padres vs Giants: Odds
The latest betting odds in Australia for Wednesday's MLB game at PETCO Park are listed below:
- Head to Head: Padres $1.48, Giants $2.70
- Line: Padres -1.5 ($2.00), Giants +1.5 ($1.83)
- Total (Over/Under 7.833 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.48 and the Giants at $2.70.
The Padres are 1.5-run favourites against the Giants, with odds of $2.00 available at TAB.
For the underdog Giants (+1.5) to cover the line, TAB offers odds of $1.83.
The over/under for total runs scored is set at 7.833 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Giants (+1.5) are predicted to cover the line 53% of the time, while the 7.833-run over/under is expected to stay under 51% of the time.
Padres vs Giants: Betting Tips
- Head to Head: San Diego at $1.48 with TAB
- Line: Giants +1.5 at $1.83 with TAB
- Total Runs: Under 7.833 at $1.91 with TAB
Stats Insider's Padres vs Giants betting tips are based on detailed simulations and wagering expertise to provide you with the best possible advice 24/7/365.
Padres vs Giants: Prediction
Stats Insider provides full betting coverage of the San Diego vs San Francisco game on Wednesday, including data-driven predictions and expert tips.
Remember, our model updates frequently, so bookmark this article for the latest betting analysis before the San Diego vs San Francisco match-up.
As always, see our Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.
Padres vs Giants: Essential Details
The game between the Padres and Giants at PETCO Park is scheduled to start at 11:40am AEST on Wednesday.
- Teams: San Diego Padres vs San Francisco Giants
- Date: Wednesday 20 August 2025
- Time: 11:40am AEST
- Venue: PETCO Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our San Diego vs San Francisco predictions are based on 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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