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Padres vs Diamondbacks Prediction and MLB Tips - 27 September 2025

The San Diego Padres will face the Arizona Diamondbacks in Game 193 of the National League Division Series at PETCO Park on Saturday, starting at 11:40am AEST.

The Padres will have Yu Darvish (4-5, 5.51 ERA) start, up against Zac Gallen (13-14, 4.70 ERA) for the Diamondbacks.

This article features Stats Insider's free betting tips for the Padres vs Diamondbacks game, along with the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Saturday's San Diego vs Arizona MLB match-up 10,000 times.

Our independent predictive analytics model currently gives the Padres a 57% chance of defeating the Diamondbacks at PETCO Park.

Padres vs Diamondbacks: Odds

The latest betting odds in Australia for Saturday's MLB game at PETCO Park are shown below:

  • Head to Head: Padres $1.77, Diamondbacks $2.10
  • Line: Padres -1.5 ($2.65), Diamondbacks +1.5 ($1.50)
  • Total (Over/Under 8 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.77 and the Diamondbacks at $2.10.

The Padres are 1.5-run favourites against the Diamondbacks, with odds of $2.65 available at TAB.

For the underdog Diamondbacks (+1.5) to cover the line, TAB offers odds of $1.50.

The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Diamondbacks (+1.5) are predicted to cover the line 61% of the time, while the 8-run over/under is expected to go over 54% of the time.

Padres vs Diamondbacks: Betting Tips

  • Head to Head: San Diego at $1.77 with TAB
  • Line: Padres -1.5 at $2.65 with TAB
  • Total Runs: Over 8 at $1.91 with TAB

These Padres vs Diamondbacks betting tips are based on market-leading simulations and wagering experience to help you place more informed bets with your chosen online bookie.

Although the Diamondbacks are more likely to cover the line, our best bet of Padres -1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the top odds available.

Padres vs Diamondbacks: Prediction

Stats Insider provides full betting coverage of the San Diego vs Arizona game on Saturday, including data-driven predictions and the best betting tips.

Remember, our model updates regularly, so refresh this article for the latest betting tips before the San Diego vs Arizona match-up.

As always, see Stats Insider's Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.

Padres vs Diamondbacks: Essential Details

The game between the Padres and Diamondbacks at PETCO Park is scheduled to begin at 11:40am AEST on Saturday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our San Diego vs Arizona predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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