Padres vs Cardinals Prediction and MLB Tips - 4 August 2025
Last updated: Aug 3, 2025, 8:10PM | Published: Aug 2, 2025, 7:31PM
The San Diego Padres will face the St. Louis Cardinals in MLB action at PETCO Park on Monday, starting at 6:10am AEST.
Dylan Cease (3-10, 4.79 ERA) will start for the Padres, while the Cardinals will counter with Andre Pallante (6-7, 4.62 ERA).
This article features Stats Insider's best betting tips for the Padres vs Cardinals game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Monday's San Diego vs St. Louis MLB match-up 10,000 times.
Our independent predictive analytics model gives the Padres a 66% chance of beating the Cardinals at PETCO Park.
Padres vs Cardinals: Odds
The current betting odds in Australia for Monday's MLB game at PETCO Park are listed below:
- Head to Head: Padres $1.49, Cardinals $2.71
- Line: Padres -1.5 ($2.09), Cardinals +1.5 ($1.76)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.49 and the Cardinals at $2.71.
The Padres are 1.5-run favourites against the Cardinals, with odds of $2.09 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.76.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 54% of the time, while the 8-run over/under is expected to stay under 54% of the time.
Padres vs Cardinals: Best Bets
- Head to Head: San Diego at $1.49 with TAB
- Line: Padres -1.5 at $2.09 with TAB
- Total Runs: Under 8 at $1.91 with TAB
Today's Padres vs Cardinals betting tips are based on detailed modelling and gambling experience to bring you the best possible advice 24/7.
Even though the Cardinals are more likely to cover the line, our best bet of Padres -1.5 is based on the likelihood of that happening, as suggested by our predictive analytics model, and the best odds available.
Padres vs Cardinals: Prediction
Stats Insider provides full betting coverage of the San Diego vs St. Louis game on Monday, including data-driven predictions and live scorestips.
Our model updates frequently, so keep checking this article for the latest betting tips before the San Diego vs St. Louis match-up.
As always, see Stats Insider's Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Padres vs Cardinals: Essential Details
The game between the Padres and Cardinals at PETCO Park is scheduled to begin at 6:10am AEST on Monday.
- Teams: San Diego Padres vs St. Louis Cardinals
- Date: Monday 4 August 2025
- Time: 6:10am AEST
- Venue: PETCO Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our San Diego vs St. Louis predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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