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Padres vs Cardinals Prediction and MLB Tips - 2 August 2025

The San Diego Padres will take on the St. Louis Cardinals in MLB action at PETCO Park on Saturday, beginning at 11:40am AEST.

Nick Pivetta (10-3, 2.81 ERA) will be on the bump for the Padres, while the Cardinals will counter with Matthew Liberatore (6-8, 4.04 ERA).

This article features Stats Insider's prediction and tips for the Padres vs Cardinals game, plus the latest betting odds in Australia.

Who Will Win?

Using trusted machine learning and data, Stats Insider has simulated the result of Saturday's San Diego vs St. Louis MLB match-up 10,000 times.

Our independent predictive analytics model gives the Padres a 65% chance of beating the Cardinals at PETCO Park.

Padres vs Cardinals: Odds

The current betting odds in Australia for Saturday's MLB game at PETCO Park are shown here:

  • Head to Head: Padres $1.48, Cardinals $2.72
  • Line: Padres -1.5 ($1.98), Cardinals +1.5 ($1.85)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.48 and the Cardinals at $2.72.

The Padres are listed as 1.5-run favourites against the Cardinals, with odds of $1.98 available at TAB.

For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.85.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 53% of the time, while the 7.5-run over/under is expected to stay under 53% of the time.

Padres vs Cardinals: Betting Tips

  • Head to Head: St. Louis at $2.72 with TAB
  • Line: Cardinals +1.5 at $1.85 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

These Padres vs Cardinals predictions are based on complex simulations and gambling intelligence to help you place more informed bets with your chosen online bookie.

While the Padres have a higher chance of winning the game, betting on the Cardinals to win is our preferred option because of the edge identified when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges seen here at Stats Insider is crucial to achieving long-term profitability.

Padres vs Cardinals: Prediction

Stats Insider provides full coverage of the San Diego vs St. Louis game on Saturday, including data-driven predictions and the best betting tips.

Our model updates frequently, so bookmark this article for the latest betting tips before the San Diego vs St. Louis game.

As always, see our Best Bets for the best tips on every MLB game, plus predictions for a wide range of other sports.

Padres vs Cardinals: Essential Details

The match-up between the Padres and Cardinals at PETCO Park is scheduled to begin at 11:40am AEST on Saturday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our San Diego vs St. Louis predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's crucial that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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