Padres vs Brewers Prediction and MLB Tips - 25 September 2025
Last updated: Sep 24, 2025, 8:11PM | Published: Sep 24, 2025, 2:28AM
The San Diego Padres will take on the Milwaukee Brewers in Game 191 of the National League Division Series at PETCO Park on Thursday, starting at 6:10am AEST.
The Padres will send Dylan Cease (8-12, 4.64 ERA) to the mound, while the Brewers are going with Chad Patrick (3-8, 3.66 ERA).
This article features Stats Insider's prediction and tips for the Padres vs Brewers game, plus the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Thursday's San Diego vs Milwaukee MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Padres a 61% chance of beating the Brewers at PETCO Park.
Padres vs Brewers: Odds
The current betting odds in Australia for Thursday's MLB game at PETCO Park are shown below:
- Head to Head: Padres $1.71, Brewers $2.20
- Line: Padres -1.5 ($2.54), Brewers +1.5 ($1.54)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Padres at $1.71 and the Brewers at $2.20.
The Padres are 1.5-run favourites against the Brewers, with odds of $2.54 available at TAB.
For the underdog Brewers (+1.5) to cover the line, TAB offers odds of $1.54.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Brewers (+1.5) are predicted to cover the line 58% of the time, while the 7.5-run over/under is expected to go over 53% of the time.
Padres vs Brewers: Betting Tips
- Head to Head: San Diego at $1.71 with TAB
- Line: Padres -1.5 at $2.54 with TAB
- Total Runs: Over 7.5 at $1.91 with TAB
If you see a 🔥, you know it's one of our best tips of the day across any sport.
Stats Insider's Padres vs Brewers betting tips are based on market-leading modelling and wagering intelligence to provide you with the best possible advice every time.
Even though the Brewers are more likely to cover the line, our best bet of Padres -1.5 is based on the likelihood of that happening, as projected by our predictive analytics model, and the top odds available.
Padres vs Brewers: Prediction
Stats Insider provides full betting coverage of the San Diego vs Milwaukee game on Thursday, including data-driven predictions and the best betting tips.
Remember, our model updates regularly, so bookmark this article for the latest betting tips before the San Diego vs Milwaukee match-up.
As always, see our Best Bets to get betting tips for every MLB game, plus predictions for a wide range of other sports.
Padres vs Brewers: Essential Details
The game between the Padres and Brewers at PETCO Park is scheduled to commence at 6:10am AEST on Thursday.
- Teams: San Diego Padres vs Milwaukee Brewers
- Date: Thursday 25 September 2025
- Time: 6:10am AEST
- Venue: PETCO Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our San Diego vs Milwaukee predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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