Orioles vs Yankees Prediction and MLB Tips - 21 September 2025
Last updated: Sep 20, 2025, 11:05PM | Published: Sep 19, 2025, 6:30PM
The Baltimore Orioles will sqaure off with the New York Yankees in Game of the League Series at Oriole Park at Camden Yards on Sunday, commencing at 9:05am AEST.
The Orioles will have Tomoyuki Sugano (10-8, 4.39 ERA) start, up against Carlos Rodón (16-9, 3.11 ERA) for the Yankees.
This article features Stats Insider's best betting tips for the Orioles vs Yankees game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the result of Sunday's Baltimore vs NY Yankees MLB match-up 10,000 times.
Our leading predictive analytics model gives the Yankees a 63% chance of beating the Orioles at Oriole Park at Camden Yards.
Orioles vs Yankees: Odds
The current betting odds in Australia for Sunday's MLB game at Oriole Park at Camden Yards are shown below:
- Head to Head: Orioles $2.65, Yankees $1.50
- Line: Orioles +1.5 ($2.00), Yankees -1.5 ($1.83)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Orioles at $2.65 and the Yankees at $1.50.
The Orioles are listed as 1.5-run underdogs against the Yankees, with odds of $2.00 available at TAB.
For the favourite Yankees (-1.5) to cover the line, TAB offers odds of $1.83.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Yankees (-1.5) are predicted to cover the line 51% of the time, while the 9-run over/under is expected to go over 52% of the time.
Orioles vs Yankees: Best Bets
- Head to Head: Baltimore at $2.65 with TAB
- Line: Orioles +1.5 at $2.00 with TAB
- Total Runs: Over 9 at $1.91 with TAB
Stats Insider's Orioles vs Yankees best bets are based on complex modelling and betting intelligence to help you place better bets with your chosen online bookie.
And while the Yankees have a higher chance of winning the game, betting on the Orioles to win is our preferred option because of the edge found when comparing our data-led probabilities to the odds currently on offer.
Taking advantage of the edges seen here at Stats Insider is one of the keys to achieving long-term profitability.
Although the Yankees are more likely to cover the line, our best bet of Orioles +1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the best odds available.
Orioles vs Yankees: Prediction
Stats Insider provides full betting coverage of the Baltimore vs NY Yankees game on Sunday, including data-driven predictions and free betting tips.
Our model updates regularly, so refresh this article for the latest betting analysis before the Baltimore vs NY Yankees match-up.
As always, see our Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.
Orioles vs Yankees: Essential Details
The game between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to start at 9:05am AEST on Sunday.
- Teams: Baltimore Orioles vs New York Yankees
- Date: Sunday 21 September 2025
- Time: 9:05am AEST
- Venue: Oriole Park at Camden Yards
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Baltimore vs NY Yankees predictions are based on 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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