Melbourne vs West Coast Prediction and Tips - AFL Round 21, 2025
Last updated: Aug 2, 2025, 3:21AM | Published: Jul 27, 2025, 10:10PM
Melbourne will face West Coast in AFL Round 21 action at Marvel Stadium on Saturday, starting at 1:20pm AEST.
This article features Stats Insider's prediction and tips for the Melbourne vs West Coast game, as well as the latest betting odds.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Saturday's Melbourne vs West Coast AFL match 10,000 times.
Our independent predictive analytics model currently gives the Demons a 96% chance of winning against the Eagles in Round 21 of the 2025 AFL season.
Melbourne vs West Coast: Odds
The latest Bet365 betting odds for Saturday's AFL clash at Marvel Stadium are listed below:
- Head to Head: Melbourne $1.05, West Coast $11.00
- Line: Melbourne -49.5 ($1.91), West Coast +49.5 ($1.91)
- Total (Over/Under 176.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has Melbourne at $1.05 and West Coast at $11.00.
The Demons are listed as 49.5-point favourites against the Eagles, with odds of $1.91 available at Bet365.
For the underdog Eagles (+49.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 176.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Eagles (+49.5) are predicted to cover the line 51% of the time, while the 176.5-point over/under is expected to stay under 54% of the time.
Melbourne vs West Coast: Best Bets
- Head to Head: Melbourne at $1.05 with Bet365
- Line: West Coast +49.5 at $1.91 with Bet365
- Total Points: Under 176.5 at $1.91 with Bet365
Stats Insider's Melbourne vs West Coast betting tips are based on market-leading modelling and wagering experience to provide you with the best possible advice 24/7/365.
Melbourne vs West Coast: Prediction
Stats Insider's predicted final score for Melbourne vs West Coast at Marvel Stadium on Saturday is Melbourne winning 111-62.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Melbourne vs West Coast match on Saturday, including data-driven predictions and live scorestips.
18+. Odds correct at time of publishing and subject to change.Remember, our model updates regularly, so refresh this page for the latest betting predictions before the Melbourne vs West Coast match.
As always, see Stats Insider's Best Bets for betting tips on every AFL match, plus predictions for a wide range of other sports.
Melbourne vs West Coast: Essential Details
The AFL Round 21 clash between the Demons and Eagles at Marvel Stadium is scheduled to commence at 1:20pm AEST on Saturday.
- Teams: Melbourne vs West Coast
- Date: Saturday 2 August 2025
- Time: 1:20pm AEST
- Venue: Marvel Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Melbourne vs West Coast predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our AFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on the AFL
Stats Insider is your home for betting on the AFL, with the latest AFL betting news, predictions for every AFL game, and futures odds for the AFL.
