Melbourne vs West Coast Prediction and Tips - AFL Round 21, 2025

Melbourne will take on West Coast in AFL Round 21 action at Marvel Stadium on Saturday, beginning at 1:20pm AEST.

This article features Stats Insider's prediction and tips for the Melbourne vs West Coast game, plus the latest betting odds.

Who Will Win?

Based on trusted computer power and data, Stats Insider has simulated the outcome of Saturday's Melbourne vs West Coast AFL match 10,000 times.

Our leading predictive analytics model currently gives the Demons a 95% chance of winning against the Eagles in Round 21 of the 2025 AFL season.

Melbourne vs West Coast: Odds

The current Bet365 betting odds for Saturday's AFL clash at Marvel Stadium are shown below:

• Head to Head: Melbourne $1.07, West Coast $8.50
• Line: Melbourne -44.5 ($1.91), West Coast +44.5 ($1.91)
• Total (Over/Under 173.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has Melbourne at $1.07 and West Coast at $8.50.

The Demons are 44.5-point favourites against the Eagles, with odds of $1.91 available at Bet365.

For the underdog Eagles (+44.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 173.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Demons (-44.5) are predicted to cover the line 51% of the time, while the 173.5-point over/under is expected to stay under 51% of the time.

Melbourne vs West Coast: Betting Tips

• Head to Head: Melbourne at $1.07 with Bet365
• Line: Melbourne -44.5 at $1.91 with Bet365
• Total Points: Under 173.5 at $1.91 with Bet365

These Melbourne vs West Coast predictions are based on detailed simulations and gambling expertise to provide you with the best possible advice around the clock.

Melbourne vs West Coast: Prediction

Stats Insider's predicted final score for Melbourne vs West Coast at Marvel Stadium on Saturday is Melbourne winning 109-63.

This prediction is based on each team's average score following 10,000 game simulations.

Stats Insider provides full coverage of the Melbourne vs West Coast match on Saturday, including data-driven predictions and live updatestips.

Remember, our model updates frequently, so keep checking this page for the latest betting predictions before the Melbourne vs West Coast match.

As always, see our Best Bets for betting tips on every AFL match, as well as predictions for a wide range of other sports.

Melbourne vs West Coast: Essential Details

The AFL Round 21 clash between the Demons and Eagles at Marvel Stadium is scheduled to start at 1:20pm AEST on Saturday.

• Teams: Melbourne vs West Coast
• Date: Saturday 2 August 2025
• Time: 1:20pm AEST
• Venue: Marvel Stadium

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Melbourne vs West Coast predictions are based on 10,000 data-driven simulations of the match, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our AFL tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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