Mariners vs Cardinals Prediction and MLB Tips - 10 September 2025
Last updated: Sep 10, 2025, 1:41AM | Published: Sep 9, 2025, 5:57AM
The Seattle Mariners will face the St. Louis Cardinals in MLB action at T-Mobile Park on Wednesday, starting at 11:40am AEST.
George Kirby (8-7, 4.47 ERA) will start on the mound for the Mariners, up against Matthew Liberatore (7-11, 4.15 ERA) for the Cardinals.
This article features Stats Insider's free betting tips for the Mariners vs Cardinals game, plus the latest betting odds in Australia.
Who Will Win?
Based on advanced computer power and data, Stats Insider has simulated the result of Wednesday's Seattle vs St. Louis MLB match-up 10,000 times.
Our leading predictive analytics model currently gives the Mariners a 63% chance of defeating the Cardinals at T-Mobile Park.
Mariners vs Cardinals: Odds
The current betting odds in Australia for Wednesday's MLB game at T-Mobile Park are listed here:
- Head to Head: Mariners $1.51, Cardinals $2.62
- Line: Mariners -1.5 ($2.03), Cardinals +1.5 ($1.80)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Mariners at $1.51 and the Cardinals at $2.62.
The Mariners are listed as 1.5-run favourites against the Cardinals, with odds of $2.03 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.80.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 55% of the time, while the 7.5-run over/under is expected to go over 53% of the time.
Mariners vs Cardinals: Betting Tips
- Head to Head: St. Louis at $2.62 with TAB
- Line: Cardinals +1.5 at $1.80 with TAB
- Total Runs: Over 7.5 at $1.91 with TAB
These Mariners vs Cardinals betting tips are based on world-class modelling and wagering experience to help you place smarter bets with your chosen online bookie.
While the Mariners have a higher chance of winning the game, betting on the Cardinals to win is our preferred option because of the edge identified when comparing our data-driven probabilities to the odds currently available.
Taking advantage of the edges published here at Stats Insider is one of the keys to achieving long-term profitability.
Mariners vs Cardinals: Prediction
Stats Insider provides full coverage of the Seattle vs St. Louis game on Wednesday, including data-driven predictions and live win probabilitiestips.
Our model updates regularly, so bookmark this page for the latest betting predictions before the Seattle vs St. Louis game.
As always, see Stats Insider's Best Bets for the best tips on every MLB game, as well as predictions for a wide range of other sports.
Mariners vs Cardinals: Essential Details
The match-up between the Mariners and Cardinals at T-Mobile Park is scheduled to start at 11:40am AEST on Wednesday.
- Teams: Seattle Mariners vs St. Louis Cardinals
- Date: Wednesday 10 September 2025
- Time: 11:40am AEST
- Venue: T-Mobile Park
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Seattle vs St. Louis predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.
