Mariners vs Cardinals Prediction and MLB Tips - 10 September 2025
Last updated: Sep 9, 2025, 5:55AM | Published: Sep 9, 2025, 5:10AM
The Seattle Mariners will sqaure off with the St. Louis Cardinals in MLB action at T-Mobile Park on Wednesday, beginning at 11:40am AEST.
George Kirby (8-7, 4.47 ERA) will start on the mound for the Mariners, up against Matthew Liberatore (7-11, 4.15 ERA) for the Cardinals.
This article features Stats Insider's prediction and tips for the Mariners vs Cardinals game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the result of Wednesday's Seattle vs St. Louis MLB game 10,000 times.
Our independent predictive analytics model currently gives the Mariners a 65% chance of winning against the Cardinals at T-Mobile Park.
Mariners vs Cardinals: Odds
The latest betting odds in Australia for Wednesday's MLB game at T-Mobile Park are shown here:
- Head to Head: Mariners $1.46, Cardinals $2.80
- Line: Mariners -1.5 ($2.06), Cardinals +1.5 ($1.78)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Mariners at $1.46 and the Cardinals at $2.80.
The Mariners are listed as 1.5-run favourites against the Cardinals, with odds of $2.06 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.78.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 55% of the time, while the 7.5-run over/under is expected to is considered an equal 50-50 chance of hitting.
Mariners vs Cardinals: Betting Tips
- Head to Head: St. Louis at $2.80 with TAB
- Line: Cardinals +1.5 at $1.78 with TAB
- Total Runs: Over 7.5 at $1.91 with TAB
Stats Insider's Mariners vs Cardinals best bets are based on complex simulations and wagering intelligence to help you place more informed bets with your chosen online bookie.
While the Mariners have a higher chance of winning the game, betting on the Cardinals to win is our preferred option because of the edge identified when comparing our data-driven probabilities to the odds currently on offer.
Taking advantage of the edges seen on Stats Insider is crucial to being profitable in the long run.
Mariners vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Seattle vs St. Louis game on Wednesday, including data-driven predictions and live updatestips.
Remember, our model updates frequently, so keep checking this article for the latest betting predictions before the Seattle vs St. Louis match-up.
As always, see Stats Insider's Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.
Mariners vs Cardinals: Essential Details
The game between the Mariners and Cardinals at T-Mobile Park is scheduled to commence at 11:40am AEST on Wednesday.
- Teams: Seattle Mariners vs St. Louis Cardinals
- Date: Wednesday 10 September 2025
- Time: 11:40am AEST
- Venue: T-Mobile Park
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Seattle vs St. Louis predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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